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Hydrocortisone / Pramoxine Topical Dosage

Medically reviewed by Drugs.com. Last updated on Jun 11, 2018.

Applies to the following strengths: 1%-1%; 2.5%-1%; 2.5%-1% with cleansing wipes; 2.35%-1%; 1.85%-1.15%; 2%-1%

Usual Adult Dose for Dermatitis

Apply as a thin film to the affected area 3 to 4 times daily

Usual Adult Dose for Psoriasis

Apply as a thin film to the affected area 3 to 4 times daily

Usual Adult Dose for Hemorrhoids

Apply as a thin film to the affected area 3 to 4 times daily

Usual Pediatric Dose for Dermatitis

Apply as a thin film to the affected area 3 to 4 times daily

Comments:
-Pediatric patients are more susceptible to systemic toxicity due to proportionally greater absorption from a greater skin surface area to body weight ratio.
-Reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing's syndrome manifestations, and intracranial hypertension have been reported in pediatric patients after systemic absorption of topically applied corticosteroids.
-Pediatric manifestations of adrenal suppression include linear growth hindrance, weight gain delayed, low plasma cortisol, and lack of response to ACTH stimulation.
-Limit use to the least amount compatible with effective therapy.

Usual Pediatric Dose for Psoriasis

Apply as a thin film to the affected area 3 to 4 times daily

Comments:
-Pediatric patients are more susceptible to systemic toxicity due to proportionally greater absorption from a greater skin surface area to body weight ratio.
-Reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing's syndrome manifestations, and intracranial hypertension have been reported in pediatric patients after systemic absorption of topically applied corticosteroids.
-Pediatric manifestations of adrenal suppression include linear growth hindrance, weight gain delayed, low plasma cortisol, and lack of response to ACTH stimulation.
-Limit use to the least amount compatible with effective therapy.

Usual Pediatric Dose for Hemorrhoids

Apply as a thin film to the affected area 3 to 4 times daily

Comments:
-Pediatric patients are more susceptible to systemic toxicity due to proportionally greater absorption from a greater skin surface area to body weight ratio.
-Reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing's syndrome manifestations, and intracranial hypertension have been reported in pediatric patients after systemic absorption of topically applied corticosteroids.
-Pediatric manifestations of adrenal suppression include linear growth hindrance, weight gain delayed, low plasma cortisol, and lack of response to ACTH stimulation.
-Limit use to the least amount compatible with effective therapy.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:
-Hypersensitivity to any of the ingredients

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-Aerosol foam: Use supplied applicator for anal administration; transfer a small amount to a tissue and rub in gently for perianal use.
-Aerosol foam: Do not insert any part of the aerosol canister directly into the anus.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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