Hydrocortisone / Pramoxine Topical Dosage
Medically reviewed by Drugs.com. Last updated on Aug 8, 2023.
Applies to the following strengths: 1%-1%; 2.5%-1%; 2.5%-1% with cleansing wipes; 2.35%-1%; 1.85%-1.15%; 2%-1%
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Dermatitis
Apply as a thin film to the affected area 3 to 4 times daily
Usual Adult Dose for Psoriasis
Apply as a thin film to the affected area 3 to 4 times daily
Usual Adult Dose for Hemorrhoids
Apply as a thin film to the affected area 3 to 4 times daily
Usual Pediatric Dose for Dermatitis
Apply as a thin film to the affected area 3 to 4 times daily
Comments:
- Pediatric patients are more susceptible to systemic toxicity due to proportionally greater absorption from a greater skin surface area to body weight ratio.
- Reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing's syndrome manifestations, and intracranial hypertension have been reported in pediatric patients after systemic absorption of topically applied corticosteroids.
- Pediatric manifestations of adrenal suppression include linear growth hindrance, weight gain delayed, low plasma cortisol, and lack of response to ACTH stimulation.
- Limit use to the least amount compatible with effective therapy.
Usual Pediatric Dose for Psoriasis
Apply as a thin film to the affected area 3 to 4 times daily
Comments:
- Pediatric patients are more susceptible to systemic toxicity due to proportionally greater absorption from a greater skin surface area to body weight ratio.
- Reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing's syndrome manifestations, and intracranial hypertension have been reported in pediatric patients after systemic absorption of topically applied corticosteroids.
- Pediatric manifestations of adrenal suppression include linear growth hindrance, weight gain delayed, low plasma cortisol, and lack of response to ACTH stimulation.
- Limit use to the least amount compatible with effective therapy.
Usual Pediatric Dose for Hemorrhoids
Apply as a thin film to the affected area 3 to 4 times daily
Comments:
- Pediatric patients are more susceptible to systemic toxicity due to proportionally greater absorption from a greater skin surface area to body weight ratio.
- Reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing's syndrome manifestations, and intracranial hypertension have been reported in pediatric patients after systemic absorption of topically applied corticosteroids.
- Pediatric manifestations of adrenal suppression include linear growth hindrance, weight gain delayed, low plasma cortisol, and lack of response to ACTH stimulation.
- Limit use to the least amount compatible with effective therapy.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
CONTRAINDICATIONS:
- Hypersensitivity to any of the ingredients
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- Aerosol foam: Use supplied applicator for anal administration; transfer a small amount to a tissue and rub in gently for perianal use.
- Aerosol foam: Do not insert any part of the aerosol canister directly into the anus.
More about hydrocortisone / pramoxine topical
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- Reviews (38)
- Side effects
- During pregnancy
- Drug class: anorectal preparations
Patient resources
- Hydrocortisone and pramoxine topical/rectal drug information
- Hydrocortisone and pramoxine (Advanced Reading)
- Pramoxine and Hydrocortisone Rectal Cream
- Pramoxine and Hydrocortisone Rectal Foam
Other brands
Proctofoam HC, Analpram E, Pramosone, Epifoam, Procort
Professional resources
- Hydrocortisone and Pramoxine Cream prescribing information
- Hydrocortisone and Pramoxine Suppository (FDA)
- Pramosone Ointment (FDA)
Other brands
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Further information
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