Skip to main content

Chloraprep One-Step Dosage

Generic name: CHLORHEXIDINE GLUCONATE 20mg in 1mL, ISOPROPYL ALCOHOL 0.7mL in 1mL
Dosage form: topical solution
Drug class: Antiseptic and germicides

Medically reviewed by Drugs.com. Last updated on Jul 2, 2025.

• use with care in premature infants or infants under 2 months of age. These products may cause irritation or chemical burns.

• use in a well ventilated area

• maximal treatment area for one applicator is approximately 8.4 in. x 8.4 in. (457 cm 2)

• remove applicator from package; do not touch sponge

• hold the applicator with the sponge down. Pinch wings only once to activate the ampule and release the antiseptic.

• wet the sponge by pressing and releasing the sponge against the treatment area until liquid is visible on the skin

• completely wet the treatment area with antiseptic

dry surgicalsites (e.g., abdomen or arm): use gentle repeated back-and-forth strokes for 30 seconds

moist surgical sites (e.g., inguinal fold): use gentle repeated back-and-forth strokes for 2 minutes

• do not allow solution to pool; tuck prep towels to absorb solution, and then remove

allow the solution to completely dry (minimum of 3 minutes on hairless skin; up to 1 hour in hair). Do not blot or wipe away.

• discard the applicator after a single use along with any portion of the solution not required to cover the prep area. It is not necessary to use the entire amount available.

Does ChloraPrep One-Step interact with my other drugs?

Enter medications to view a detailed interaction report using our Drug Interaction Checker.

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.