Brompheniramine / Dextromethorphan / Phenylephrine Dosage

Medically reviewed by Drugs.com. Last updated on Sep 7, 2023.

Applies to the following strengths: 1 mg-5 mg-2.5 mg/5 mL; 10 mg-30 mg-25 mg/5 mL; 2 mg-10 mg-5 mg/5 mL; 4 mg-15 mg-7.5 mg/5 mL; 4 mg-20 mg-10 mg/5 mL; 2 mg-15 mg-7.5 mg/5 mL; 8 mg-20 mg-20 mg/5 mL

Usual Adult Dose for Cough and Nasal Congestion

Brompheniramine 1 mg/ dextromethorphan 5 mg/ phenylephrine 2.5 mg per 5 mL liquid: 20 mL every 4 hours
Maximum dose: 6 doses per 24 hours

Brompheniramine 2 mg/ dextromethorphan 10 mg/ phenylephrine 5 mg per 10 mL liquid: 20 mL every 4 hours
Maximum dose: 6 doses per 24 hours

Brompheniramine 4 mg/ dextromethorphan 20 mg/ phenylephrine 10 mg per 5 mL liquid: 5 mL every 4 hours
Maximum dose: 6 doses per 24 hours

Usual Pediatric Dose for Cough and Nasal Congestion

Brompheniramine 1 mg/ dextromethorphan 5 mg/ phenylephrine 2.5 mg per 5 mL liquid:
12 years and older: 20 mL every 4 hours
6 to under 12 years: 10 mL every 4 hours
Maximum dose: 6 doses per 24 hours

Brompheniramine 2 mg/ dextromethorphan 10 mg/ phenylephrine 5 mg per 10 mL liquid:
12 years and older: 20 mL every 4 hours
6 to under 12 years: 10 mL every 4 hours
Maximum dose: 6 doses per 24 hours

Brompheniramine 4 mg/ dextromethorphan 20 mg/ phenylephrine 10 mg per 5 mL liquid:
12 years and older: 5 mL every 4 hours
6 to under 12 years: 2.5 mL every 4 hours
Maximum dose: 6 doses per 24 hours

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

Current use of a monoamine oxidase inhibitor (MAOI) or use within 14 days of stopping a MAOI.
Use in children under 2 years old.

Safety and efficacy have not been established in patients younger than 6 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

Use only the provided dosing cups for measuring.

Patient advice:

Take only as directed.
Avoid drinking alcohol while on this drug.
Discontinue for nervousness, dizziness, or sleepiness.
Use caution if driving a motor vehicle or operating machinery.
If symptoms last over 7 days or are accompanied by fever, seek medical attention.
If cough lasts over 7 days or comes back, or is accompanied or followed by fever, headache that lasts, or rash, seek medical care promptly.