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Atropine / Pralidoxime Dosage

Medically reviewed by Drugs.com. Last updated on Jul 19, 2024.

Applies to the following strengths: 2.1 mg/0.7 mL-600 mg/2 mL

Usual Adult Dose for Organophosphate Poisoning

DuoDote(R) autoinjector:

Mild symptoms in patients over 41 kg, patient has 2 or more mild symptoms of poisoning:
First dose: 1 injection intramuscularly into the mid-lateral thigh


Severe symptoms in patients over 41 kg:
Give 3 injections intramuscularly in rapid succession in the mid-lateral thigh

ATNAA(R):

Self aid: Administer 1 injection into the lateral thigh muscle or buttocks

Buddy aid: For patients with severe symptoms:


Mild symptoms:

Severe symptoms:


Comments:

Use(s): Poisoning by organophosphorous nerve agents and organophosphorous insecticides.

Usual Adult Dose for Nerve Agent Poisoning

DuoDote(R) autoinjector:

Mild symptoms in patients over 41 kg, patient has 2 or more mild symptoms of poisoning:
First dose: 1 injection intramuscularly into the mid-lateral thigh


Severe symptoms in patients over 41 kg:
Give 3 injections intramuscularly in rapid succession in the mid-lateral thigh

ATNAA(R):

Self aid: Administer 1 injection into the lateral thigh muscle or buttocks

Buddy aid: For patients with severe symptoms:


Mild symptoms:

Severe symptoms:


Comments:

Use(s): Poisoning by organophosphorous nerve agents and organophosphorous insecticides.

Usual Pediatric Dose for Organophosphate Poisoning

DuoDote(R) autoinjector:

Mild symptoms in patients over 41 kg, patient has 2 or more mild symptoms of poisoning:
First dose: 1 injection intramuscularly into the mid-lateral thigh


Severe symptoms in patients over 41 kg:
Give 3 injections intramuscularly in rapid succession in the mid-lateral thigh

Mild symptoms:

Severe symptoms:

Comments:

Use(s): Poisoning by organophosphorous nerve agents and organophosphorous insecticides.

Usual Pediatric Dose for Nerve Agent Poisoning

DuoDote(R) autoinjector:

Mild symptoms in patients over 41 kg, patient has 2 or more mild symptoms of poisoning:
First dose: 1 injection intramuscularly into the mid-lateral thigh


Severe symptoms in patients over 41 kg:
Give 3 injections intramuscularly in rapid succession in the mid-lateral thigh

Mild symptoms:

Severe symptoms:

Comments:

Use(s): Poisoning by organophosphorous nerve agents and organophosphorous insecticides.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:


Safety and efficacy have not been established in patients weighing under 41 kg.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.