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Atropine / Pralidoxime Dosage

Medically reviewed by Drugs.com. Last updated on Jul 19, 2024.

Applies to the following strengths: 2.1 mg/0.7 mL-600 mg/2 mL

Usual Adult Dose for Organophosphate Poisoning

DuoDote(R) autoinjector:

Mild symptoms in patients over 41 kg, patient has 2 or more mild symptoms of poisoning:
First dose: 1 injection intramuscularly into the mid-lateral thigh


Severe symptoms in patients over 41 kg:
Give 3 injections intramuscularly in rapid succession in the mid-lateral thigh

ATNAA(R):

Self aid: Administer 1 injection into the lateral thigh muscle or buttocks

Buddy aid: For patients with severe symptoms:


Mild symptoms:

Severe symptoms:


Comments:

Use(s): Poisoning by organophosphorous nerve agents and organophosphorous insecticides.

Usual Adult Dose for Nerve Agent Poisoning

DuoDote(R) autoinjector:

Mild symptoms in patients over 41 kg, patient has 2 or more mild symptoms of poisoning:
First dose: 1 injection intramuscularly into the mid-lateral thigh


Severe symptoms in patients over 41 kg:
Give 3 injections intramuscularly in rapid succession in the mid-lateral thigh

ATNAA(R):

Self aid: Administer 1 injection into the lateral thigh muscle or buttocks

Buddy aid: For patients with severe symptoms:


Mild symptoms:

Severe symptoms:


Comments:

Use(s): Poisoning by organophosphorous nerve agents and organophosphorous insecticides.

Usual Pediatric Dose for Organophosphate Poisoning

DuoDote(R) autoinjector:

Mild symptoms in patients over 41 kg, patient has 2 or more mild symptoms of poisoning:
First dose: 1 injection intramuscularly into the mid-lateral thigh


Severe symptoms in patients over 41 kg:
Give 3 injections intramuscularly in rapid succession in the mid-lateral thigh

Mild symptoms:

Severe symptoms:

Comments:

Use(s): Poisoning by organophosphorous nerve agents and organophosphorous insecticides.

Usual Pediatric Dose for Nerve Agent Poisoning

DuoDote(R) autoinjector:

Mild symptoms in patients over 41 kg, patient has 2 or more mild symptoms of poisoning:
First dose: 1 injection intramuscularly into the mid-lateral thigh


Severe symptoms in patients over 41 kg:
Give 3 injections intramuscularly in rapid succession in the mid-lateral thigh

Mild symptoms:

Severe symptoms:

Comments:

Use(s): Poisoning by organophosphorous nerve agents and organophosphorous insecticides.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:


Safety and efficacy have not been established in patients weighing under 41 kg.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.