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Vericiguat Disease Interactions

There are 2 disease interactions with vericiguat:

Moderate

Vericiguat (Includes vericiguat) hepatic impairment

Moderate Potential Hazard, Moderate plausibility. Applies to: Liver Disease

Vericiguat has not been studied in patients with severe hepatic impairment (Child-Pugh C). Caution is advised. No dosage adjustment is recommended in patients with mild or moderate hepatic impairment (Child-Pugh A or B).

Moderate

Vericiguat (Includes vericiguat) renal impairment

Moderate Potential Hazard, Moderate plausibility. Applies to: Renal Dysfunction

Vericiguat has not been studied in patients with eGFR <15 mL/min/1.73m2 or on dialysis. Caution is advised. No dose adjustment is required for patients with eGFR >15 mL/min/1.73m2 not on dialysis.

Vericiguat drug interactions

There are 5 drug interactions with vericiguat

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.