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Vericiguat Dosage

Medically reviewed by Last updated on Jan 25, 2024.

Applies to the following strengths: 2.5 mg; 5 mg; 10 mg

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Heart Failure

Initial dose: 2.5 mg orally once a day
Maintenance dose: The dose should be doubled about every 2 weeks to reach the target dose of 10 mg orally once a day, as tolerated by the patient.

Use: To reduce the risk of cardiovascular death and heart failure (HF) hospitalization after a hospitalization for HF or need for outpatient IV diuretics, in patients with symptomatic chronic HF and ejection fraction less than 45%

Renal Dose Adjustments

Estimated GFR at least 15 mL/min/1.73 m2 (not on dialysis): No adjustment recommended.
Estimated GFR less than 15 mL/min/1.73 m2: Data not available


Liver Dose Adjustments

Mild or moderate liver dysfunction (e.g., Child-Pugh A or B): No dose adjustment recommended.
Severe liver dysfunction (e.g., Child-Pugh C): Data not available





Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.


Data not available


Other Comments

Administration advice:

Storage requirements:


Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.