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Varicella zoster immune globulin Disease Interactions

There is 1 disease interaction with varicella zoster immune globulin.

Moderate

Varicella zoster immune globulin (applies to varicella zoster immune globulin) thrombotic events

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Cardiovascular Disease, Coagulation Defect, Heart Disease, History - Thrombotic/Thromboembolic Disorder, Thrombocytopenia

Thrombotic events may occur during or after treatment with varicella zoster immune globulin. At-risk patients include those with history of atherosclerosis, multiple cardiovascular risk factors, advanced age, impaired cardiac output, coagulation disorders, prolonged periods of immobilization, and/or known/suspected hyperviscosity. Baseline assessment of blood viscosity should be considered in patients at risk for hyperviscosity (including patients with cryoglobulins, fasting chylomicronemia/markedly high triacylglycerols [triglycerides], or monoclonal gammopathies). Varicella zoster immune globulin should be administered IM only. In patients with severe thrombocytopenia or any coagulation disorder that would contraindicate IM injections, varicella zoster immune globulin should be administered only if the expected benefits outweigh the potential risks.

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Varicella zoster immune globulin drug interactions

There are 22 drug interactions with varicella zoster immune globulin.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

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