Varicella zoster immune globulin Pregnancy and Breastfeeding Warnings

Brand names: VariZIG

Medically reviewed by Drugs.com. Last updated on Dec 17, 2024.

Varicella zoster immune globulin Pregnancy Warnings

This drug should be used during pregnancy only if clearly needed; caution is recommended.

AU TGA pregnancy category: Not formally assigned to a pregnancy category.
US FDA pregnancy category: Not assigned

Risk summary: No data are available on the use of this drug in pregnant women to inform a drug-related risk.

Comments:
-According to some authorities: No harmful effects on pregnancy, the fetus, or the neonate are expected based on clinical experience with immunoglobulins.

Animal studies have not been reported. There are no controlled data in human pregnancy.

US FDA pregnancy category Not Assigned: The US FDA has amended the pregnancy labeling rule for prescription drug products to require labeling that includes a summary of risk, a discussion of the data supporting that summary, and relevant information to help health care providers make prescribing decisions and counsel women about the use of drugs during pregnancy. Pregnancy categories A, B, C, D, and X are being phased out.

See references

Varicella zoster immune globulin Breastfeeding Warnings

No special precautions are needed while breastfeeding.
-According to some authorities: Caution is recommended.

Excreted into human milk: Unknown
Excreted into animal milk: Data not available

Comments:
-No information is available on the clinical use of this drug during breastfeeding.
-Immunoglobulins are excreted into milk and may contribute to protecting neonates from pathogens with a mucosal portal of entry.
-This drug is an immune globulin, rich in immunoglobulin G (IgG) antibodies against varicella zoster virus.
-IgG is a normal component of breast milk; it is likely to be partially destroyed in the infant's gastrointestinal tract and poorly absorbed by the infant during nursing.
-This drug can be administered IM to infants weighing less than 2 kg.

See references

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer