Tisotumab vedotin Disease Interactions
There are 3 disease interactions with tisotumab vedotin.
Tisotumab vedotin (applies to tisotumab vedotin) hepatic impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
Avoid the use of tisotumab vedotin in patients with moderate or severe hepatic impairment.
Tisotumab vedotin (applies to tisotumab vedotin) ocular toxicity
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Visual Defect/Disturbance
Ocular adverse events are very common in patients receiving treatment with tisotumab vedotin. Patients with baseline visual disturbances should be monitored and if any symptoms worsen should be evaluated promptly by an eye care provider. Reduce dosage, withhold or permanently discontinue treatment based on the severity of the symptoms.
Tisotumab vedotin (applies to tisotumab vedotin) peripheral neuropathy
Moderate Potential Hazard, Moderate plausibility.
Patients receiving treatment with tisotumab vedotin may have peripheral neuropathy adverse reactions. Patients with preexisting peripheral neuropathy should be monitored. Reduce dosage, withhold, or permanently discontinue treatment based on the severity of symptoms.
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Tisotumab vedotin drug interactions
There are 321 drug interactions with tisotumab vedotin.
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- Drug class: miscellaneous antineoplastics
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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