Tarlatamab Disease Interactions
There are 2 disease interactions with tarlatamab.
Moderate
Tarlatamab (applies to tarlatamab) hepatic dysfunction
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
The effects of moderate to severe hepatic impairment on the pharmacokinetics of tarlatamab are unknown.
References (1)
- (2024) "Product Information. Imdelltra (tarlatamab)." Amgen USA
Moderate
Tarlatamab (applies to tarlatamab) renal dysfunction
Moderate Potential Hazard, Moderate plausibility.
The effects of severe renal impairment (eGFR 15 to 29 mL/min) and end-stage renal disease (eGFR less than 15 mL/min) on the pharmacokinetics of tarlatamab are unknown.
References (1)
- (2024) "Product Information. Imdelltra (tarlatamab)." Amgen USA
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Tarlatamab drug interactions
There are 364 drug interactions with tarlatamab.
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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