Tarlatamab Disease Interactions
There are 2 disease interactions with tarlatamab.
Tarlatamab (applies to tarlatamab) hepatic dysfunction
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
The effects of moderate to severe hepatic impairment on the pharmacokinetics of tarlatamab are unknown.
Tarlatamab (applies to tarlatamab) renal dysfunction
Moderate Potential Hazard, Moderate plausibility.
The effects of severe renal impairment (eGFR 15 to 29 mL/min) and end-stage renal disease (eGFR less than 15 mL/min) on the pharmacokinetics of tarlatamab are unknown.
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Tarlatamab drug interactions
There are 358 drug interactions with tarlatamab.
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- Drug class: bispecific T-cell engagers (BiTE)
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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