Spesolimab Disease Interactions

Spesolimab may increase the risk of infections and should not be initiated in patients having any active infection, including tuberculosis (TB), until it is appropriately treated and resolved. Patients should be evaluated for TB prior to treatment and anti-tuberculosis treatment should be considered in patients with latent TB or history of TB with unconfirmed adequate treatment. In patients with chronic or recurrent infections, risk and benefits of treatment with this drug should be carefully assessed. Patients receiving this drug should be advised to contact their health care provider if they have any signs or symptoms of infection during or after treatment.