Rezdiffra Disease Interactions
There is 1 disease interaction with Rezdiffra (resmetirom).
Resmetirom (applies to Rezdiffra) liver dysfunction
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
Avoid use of resmetirom in patients with decompensated cirrhosis (consistent with moderate to severe liver dysfunction [Child-Pugh B or C]); drug exposure and the risk of adverse reactions are increased in this population. The safety and effectiveness of resmetirom has not been established in patients with NASH cirrhosis. No dosage adjustment is recommended for patients with mild liver dysfunction (Child-Pugh A). Monitor patients during treatment with resmetirom for elevations in liver tests and for the development of liver-related adverse reactions.
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Rezdiffra drug interactions
There are 145 drug interactions with Rezdiffra (resmetirom).
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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