Yodefan Disease Interactions
There are 4 disease interactions with Yodefan (potassium iodide).
Iodide salts (applies to Yodefan) hyperthyroidism
Moderate Potential Hazard, Low plausibility.
The use of iodide salts has been associated with the exacerbation or precipitation of hyperthyroidism in patients previously euthyroid. Induction of goiter has been reported in patients with hyperthyroidism. Iodide salts should be administered cautiously in patients with hyperthyroidism.
References (8)
- Iancu T, Boyanower Y, Laurian N (1974) "Congenital goiter due to maternal ingestion of iodide." Am J Dis Child, 128, p. 528-30
- Ayromlooi J (1972) "Congenital goiter due to maternal ingestion of iodides." Obstet Gynecol, 39, p. 818-22
- Denham MJ, Himsworth RL (1974) "Hyperthyroidism induced by potassium iodide given in the course of 125I-fibrinogen test." Age Ageing, 3, p. 221-5
- Yalow RS (1983) "Risks in mass distribution of potassium iodide." Bull N Y Acad Med, 59, p. 1020-7
- "Product Information. SSKI (saturated) (potassium iodide)." Upsher-Smith Laboratories Inc
- (2022) "Product Information. Pima (potassium iodide)." Fleming and Company
- Carswell F, Kerr MM, Hutchison JH (1970) "Congenital goitre and hypothyroidism produced by maternal ingestion of iodides." Lancet, 1, p. 1241-3
- Parmelle A, et al. (1940) "Three cases of newborn infants with congential goiter due to ingestion of iodide." Am J Obstet Gynecol, 40, p. 145-7
Potassium iodide (applies to Yodefan) heart disease
Moderate Potential Hazard, Moderate plausibility.
Potassium iodide should not be used in patients that have nodular thyroid disease and heart disease. Patients experiencing irregular heartbeats or chest pain should be instructed to stop treatment with potassium iodide.
References (2)
- "Product Information. SSKI (saturated) (potassium iodide)." Upsher-Smith Laboratories Inc
- (2022) "Product Information. Pima (potassium iodide)." Fleming and Company
Potassium iodide (applies to Yodefan) dermatitis herpetiformis
Moderate Potential Hazard, Moderate plausibility.
Potassium iodide should not be used in patients that have or have ever had dermatitis herpetiformis.
References (2)
- "Product Information. SSKI (saturated) (potassium iodide)." Upsher-Smith Laboratories Inc
- (2022) "Product Information. Pima (potassium iodide)." Fleming and Company
Potassium iodide (applies to Yodefan) vasculitis
Moderate Potential Hazard, Moderate plausibility.
People who are allergic to iodide or have hypocomplementemic vasculitis should not take potassium iodide.
References (2)
- "Product Information. SSKI (saturated) (potassium iodide)." Upsher-Smith Laboratories Inc
- (2022) "Product Information. Pima (potassium iodide)." Fleming and Company
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Yodefan drug interactions
There are 50 drug interactions with Yodefan (potassium iodide).
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More about Yodefan (potassium iodide)
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- During pregnancy
- Drug class: antithyroid agents
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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