Parathyroid hormone Disease Interactions
There are 3 disease interactions with parathyroid hormone.
Parathyroid hormone/analogs (applies to parathyroid hormone) hyperparathyroidism
Major Potential Hazard, Moderate plausibility. Applicable conditions: Hypercalcemia
Patients known to have an underlying hypercalcemic disorder, such as primary hyperparathyroidism, should not be treated with parathyroid hormone and its analogs because of the risk of exacerbating hypercalcemia.
Parathyroid hormone/analogs (applies to parathyroid hormone) malignancy
Major Potential Hazard, Moderate plausibility. Applicable conditions: Paget's Disease, Neoplasm of Bone
Parathyroid hormone and its analogs should not be used in patients who are at increased baseline risk for osteosarcoma. These agents should only be used if the potential benefits are considered to outweigh the potential risks. Monitor these patients according to clinical guidelines. Patients with bone metastases or a history of skeletal malignancies should not be treated with these agents.
Parathyroid hormone (applies to parathyroid hormone) renal impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction
Parathyroid hormone is eliminated by the kidney and maximum drug levels increased with renal impairment. No dose adjustment is recommended in patients with mild to moderate renal impairment. No studies have been conducted in patients with severe renal impairment or in renal impairment patients on dialysis. Care and close monitoring should be exercised when using this agent in patients with severe renal impairment or on dialysis.
Parathyroid hormone drug interactions
There are 5 drug interactions with parathyroid hormone.
More about parathyroid hormone
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- During pregnancy
- Drug class: parathyroid hormone and analogs
- Breastfeeding
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.