Neosporin + Pain Relief Cream Disease Interactions
There are 2 disease interactions with Neosporin + Pain Relief Cream (neomycin / polymyxin b / pramoxine topical).
Neomycin (otic) (applies to Neosporin + Pain Relief Cream) perforated tympanic membrane
Major Potential Hazard, High plausibility.
Like other aminoglycosides, neomycin is potentially ototoxic, both to vestibular and to auditory functions. Therapy with neomycin otic preparations should be administered cautiously in patients with chronic otitis media or a perforated tympanic membrane. The risk of ototoxicity may be increased if medication enters the middle ear.
References (1)
- (2001) "Product Information. Mycifradin (neomycin)." Emerson Laboratories
Topical aminoglycosides (applies to Neosporin + Pain Relief Cream) burns
Moderate Potential Hazard, High plausibility. Applicable conditions: Burns - External
Topical aminoglycosides should not be used on serious burns. When applied locally, aminoglycosides are generally not absorbed to a significant extent through intact skin but readily absorbed through denuded, burned, or granulating skin. Systemic adverse effects of aminoglycosides include nephrotoxicity and ototoxicity to vestibular and auditory functions. In general, topical aminoglycosides should not be used on large areas of the body or for more than 7 days without medical supervision.
References (1)
- (2001) "Product Information. Myciguent (neomycin topical)." Pharmacia and Upjohn
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Neosporin + Pain Relief Cream drug interactions
There are 71 drug interactions with Neosporin + Pain Relief Cream (neomycin / polymyxin b / pramoxine topical).
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More about Neosporin + Pain Relief Cream (neomycin / polymyxin b / pramoxine topical)
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- Drug class: topical antibiotics
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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