Lifileucel Disease Interactions

Patients treated with lifileucel have exhibited cardiac disorders. Prior to administration of lifileucel, assess patients for a history of cardiac/vascular disorders or for current use of anticoagulants. Monitor patients with signs and symptoms of cardiac disorders before and after infusion of lifileucel.

Lifeleucel should not be administered to patients with active infection or inflammatory disorders. Monitor patients for signs or symptoms of infection before and after infusion of lifileucel; treat appropriately as indicated. Administer prophylactic antimicrobials according to institutional guidelines.

Patients treated with lifileucel may develop worsened renal function. Prior to administration of lifileucel, assess patients for a history of renal impairment. Monitor patients with signs and symptoms of acute renal failure before and after infusion of lifileucel. Withhold or discontinue lifileucel infusion if severe acute renal injury is evidenced.

Patients treated with lifileucel may develop worsened respiratory function. Prior to administration of lifileucel, assess patients for a history of respiratory disorders. Monitor patients with signs and symptoms of respiratory failure before and after infusion of lifileucel. Withhold or discontinue lifileucel infusion if severe acute respiratory failure is evidenced.