Lifileucel Disease Interactions
There are 4 disease interactions with lifileucel.
Lifileucel (applies to lifileucel) cardiac/vascular disorders
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Heart Disease, Cardiovascular Disease, History - Myocardial Infarction
Patients treated with lifileucel have exhibited cardiac disorders. Prior to administration of lifileucel, assess patients for a history of cardiac/vascular disorders or for current use of anticoagulants. Monitor patients with signs and symptoms of cardiac disorders before and after infusion of lifileucel.
Lifileucel (applies to lifileucel) infections
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Infection - Bacterial/Fungal/Protozoal/Viral
Lifeleucel should not be administered to patients with active infection or inflammatory disorders. Monitor patients for signs or symptoms of infection before and after infusion of lifileucel; treat appropriately as indicated. Administer prophylactic antimicrobials according to institutional guidelines.
Lifileucel (applies to lifileucel) renal impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction
Patients treated with lifileucel may develop worsened renal function. Prior to administration of lifileucel, assess patients for a history of renal impairment. Monitor patients with signs and symptoms of acute renal failure before and after infusion of lifileucel. Withhold or discontinue lifileucel infusion if severe acute renal injury is evidenced.
Lifileucel (applies to lifileucel) respiratory disorders
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Pulmonary Impairment
Patients treated with lifileucel may develop worsened respiratory function. Prior to administration of lifileucel, assess patients for a history of respiratory disorders. Monitor patients with signs and symptoms of respiratory failure before and after infusion of lifileucel. Withhold or discontinue lifileucel infusion if severe acute respiratory failure is evidenced.
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Lifileucel drug interactions
There are 268 drug interactions with lifileucel.
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- Drug class: miscellaneous antineoplastics
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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