Itovebi Disease Interactions
There are 3 disease interactions with Itovebi (inavolisib).
Inavolisib (applies to Itovebi) diabetes
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Diabetes Mellitus
Treatment with inavolisib may cause severe hyperglycemia. The safety of inavolisib in patients with type 1 diabetes mellitus or type 2 diabetes mellitus requiring ongoing antihyperglycemic treatment have not been studied. Patients with a history of well-controlled type 2 diabetes mellitus may require intensified antihyperglycemic treatment and close monitoring of fasting glucose levels.
Inavolisib (applies to Itovebi) hepatic impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
Inavolisib has not been studied in patients with moderate to severe hepatic impairment.
Inavolisib (applies to Itovebi) renal impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction
Use of inavolisib has not been evaluated in patients with severe renal impairment (estimated GFR less than 30 mL/min). Dose reduction is recommended in patients with moderate renal impairment (estimated GFR 30 to less than 60 mL/min) due to significantly increased exposure.
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Itovebi drug interactions
There are 218 drug interactions with Itovebi (inavolisib).
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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