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Vascepa Disease Interactions

There are 3 disease interactions with Vascepa (icosapent).

Moderate

Icosapent (applies to Vascepa) atrial fibrillation/flutter

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Arrhythmias

Icosapent is associated with an increased risk of atrial fibrillation or atrial flutter requiring hospitalization. In a cardiovascular outcomes trial, the incidence of atrial fibrillation was greater in patients with history of atrial fibrillation or atrial flutter; caution is recommended in these patients.

References (1)
  1. (2019) "Product Information. Vascepa (icosapent)." Amarin Pharmaceuticals Inc, SUPPL-35
Moderate

Icosapent (applies to Vascepa) fish allergy

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Allergies

Icosapent ethyl is obtained from the oil of fish. It is unknown if patients with allergies to fish and/or shellfish are at increased risk of an allergic reaction to this drug. Use with caution in patients with known hypersensitivity to fish and/or shellfish; advise such patients about the potential for allergic reactions to this drug.

References (1)
  1. (2019) "Product Information. Vascepa (icosapent)." Amarin Pharmaceuticals Inc, SUPPL-35
Moderate

Icosapent (applies to Vascepa) liver disease

Moderate Potential Hazard, Moderate plausibility.

In patients with liver dysfunction, ALT and AST levels should be monitored periodically during therapy with icosapent; caution is recommended in these patients.

References (1)
  1. (2019) "Product Information. Vascepa (icosapent)." Amarin Pharmaceuticals Inc, SUPPL-35

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Vascepa drug interactions

There are 76 drug interactions with Vascepa (icosapent).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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