Guanidine Hydrochloride (guanidine) Disease Interactions
There is 1 disease interaction with Guanidine Hydrochloride (guanidine):
Guanidine (Includes Guanidine Hydrochloride) ↔ bone marrow suppression
Severe Potential Hazard, High plausibility. Applies to: Bone Marrow Depression/Low Blood Counts
The use of guanidine has been rarely associated with dose-related bone marrow suppression, sometimes fatal. Therapy with guanidine should be administered cautiously in patients with preexisting bone marrow suppression. Monitoring complete blood cell counts (CBC) and differential counts at baseline and periodically is recommended. Discontinue guanidine if bone marrow suppression occurs. Patients should be instructed to immediately report any signs or symptoms suggesting bone marrow suppression, such as fever, sore throat, local infection, bleeding, or symptoms of anemia.
- "Product Information. Guanidine (guanidine)." Schering Corporation, Kenilworth, NJ.
Guanidine Hydrochloride (guanidine) drug interactions
There are 84 drug interactions with Guanidine Hydrochloride (guanidine)
More about Guanidine Hydrochloride (guanidine)
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
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