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Guanidine Hydrochloride (guanidine) Disease Interactions

There is 1 disease interaction with Guanidine Hydrochloride (guanidine):

Major

Guanidine (Includes Guanidine Hydrochloride) ↔ bone marrow suppression

Severe Potential Hazard, High plausibility. Applies to: Bone Marrow Depression/Low Blood Counts

The use of guanidine has been rarely associated with dose-related bone marrow suppression, sometimes fatal. Therapy with guanidine should be administered cautiously in patients with preexisting bone marrow suppression. Monitoring complete blood cell counts (CBC) and differential counts at baseline and periodically is recommended. Discontinue guanidine if bone marrow suppression occurs. Patients should be instructed to immediately report any signs or symptoms suggesting bone marrow suppression, such as fever, sore throat, local infection, bleeding, or symptoms of anemia.

References

  1. "Product Information. Guanidine (guanidine)." Schering Corporation, Kenilworth, NJ.

Guanidine Hydrochloride (guanidine) drug interactions

There are 84 drug interactions with Guanidine Hydrochloride (guanidine)

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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