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Guanidine Side Effects

Medically reviewed by Last updated on May 12, 2022.

Applies to guanidine: oral tablet.

Guanidine can increase your risk of bleeding or infection. Call your doctor if you have unusual bruising or bleeding, or new signs of infection (fever, chills, tiredness, mouth sores).

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe or ongoing stomach problems;

  • a light-headed feeling, like you might pass out;

  • painful urination, blood or pus in your urine;

  • fast or pounding heartbeats;

  • confusion, hallucinations, unusual thoughts or behavior;

  • problems with balance or muscle movement;

  • tremors; or

  • low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.

Common side effects may include:

  • nausea, diarrhea, stomach cramps;

  • numbness or tingling (especially in your face, hands, or feet);

  • feeling nervous or irritable;

  • abnormal liver function tests;

  • flushing (sudden warmth, redness, or tingly feeling);

  • dry mouth, upset stomach, loss of appetite;

  • sweating, rash, dry or scaly skin; or

  • redness or crusting around your hair follicles.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.