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Ferumoxytol Disease Interactions

There are 2 disease interactions with ferumoxytol.

Moderate

Ferrous salts (applies to ferumoxytol) hypersensitivity reactions

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Allergies

Serious hypersensitivity reactions, including anaphylaxis- type reactions, some of which have been life-threatening have been reported in patients using some injection iron products. Patients may present with shock, clinically significant hypotension, loss of consciousness, and/or collapse. These products should be administered cautiously, especially in patients with a history of significant allergies. Patients should be monitored during and at least 30 minutes after the administration. Epinephrine should be immediately available in the event of acute hypersensitivity reactions.

References

  1. "Product Information. Feraheme (ferumoxytol)." Alza Pharmaceuticals (2009):
  2. "Product Information. Injectafer (ferric carboxymaltose)." American Regent Laboratories Inc (2013):
Moderate

Ferumoxytol (applies to ferumoxytol) hypotension

Moderate Potential Hazard, Moderate plausibility.

Clinically significant hypotension has been reported in clinical trials and postmarketing after the administration of ferumoxytol injection. Patients should be monitored for signs and symptoms of hypotension after administration.

References

  1. "Product Information. Feraheme (ferumoxytol)." Alza Pharmaceuticals (2009):

Ferumoxytol drug interactions

There are 28 drug interactions with ferumoxytol.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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