Ergoloid mesylates Disease Interactions
There are 2 disease interactions with ergoloid mesylates:
Amine ergots (Includes ergoloid mesylates) ↔ cardiovascular adverse effects
Severe Potential Hazard, Moderate plausibility. Applies to: Tachyarrhythmia
The amine ergot alkaloids, ergonovine and methylergonovine, can cause serious cardiovascular complications because of their vasospastic effects. Hypertension (more often with ergonovine) has been most commonly reported, particularly when administered IV undiluted or at an excessive rate or when used in conjunction with regional anesthesia or vasoconstrictors. Headaches, seizures, cerebrovascular accidents and death have been associated with the hypertensive episodes. Other, less common adverse effects include acute myocardial infarction, transient chest pains, thrombophlebitis, tachycardia and palpitations. Therapy with ergot alkaloids should generally be avoided, except under special circumstances, in patients with chronic hypertension, preeclampsia or eclampsia, cardiovascular disease, cerebrovascular disease, or peripheral vascular disease. Caution is advised when these agents are administered to patients with venoatrial shunts, mitral valve stenosis, or sepsis. Close monitoring of cardiovascular status is highly recommended during therapy.
- "Product Information. Ergotrate Maleate (ergonovine)." Bedford, Bedford, OH.
- American Medical Association, Division of Drugs and Toxicology "Drug evaluations annual 1994." Chicago, IL: American Medical Association; (1994):
Ergoloid mesylates (Includes ergoloid mesylates) ↔ psychosis
Severe Potential Hazard, Moderate plausibility. Applies to: Psychosis
The use of ergoloid mesylates is contraindicated in patients with acute or chronic psychosis, regardless of etiology.
- "Product Information. Gerimal (ergoloid mesylates)." Novartis Pharmaceuticals, East Hanover, NJ.
Ergoloid mesylates drug interactions
There is 1 drug interaction with ergoloid mesylates
More about ergoloid mesylates
- Ergoloid mesylates Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Pricing & Coupons
- En Español
- Drug class: miscellaneous central nervous system agents
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
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