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Ergoloid mesylates

Generic name: ergoloid mesylates [ ER-goe-loyd-MES-i-lates ]
Brand names: Hydergine, Hydergine LC
Dosage forms: compounding powder (-), oral tablet (1 mg)
Drug class: Miscellaneous central nervous system agents

Medically reviewed by on Aug 16, 2023. Written by Cerner Multum.

What is ergoloid mesylates?

Ergoloid mesylates is used to improve cognitive (mental) and self-care functioning in people with symptoms of dementia related to aging or conditions such as Alzheimer's disease.

Ergoloid mesylates is not a cure for dementia or for any underlying disease that may lead to decreased mental capacity.

Ergoloid mesylates will not treat dementia that is related to mental illness, mood disorders, or neurologic disease.

Ergoloid mesylates may also be used for purposes not listed in this medication guide.

Ergoloid mesylates side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Ergoloid mesylates may cause serious side effects. Call your doctor at once if you have:

Common side effects of ergoloid mesylates may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


You should not take ergoloid mesylates if you have a history of mental illness or psychosis.

Before taking this medicine

You should not take ergoloid mesylates if you are allergic to it, or if you have:

It is not known whether ergoloid mesylates will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using ergoloid mesylates.

It is not known whether ergoloid mesylates passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I use ergoloid mesylates?

Ergoloid mesylates is usually taken 3 times per day. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Your doctor will need to check your progress at regular visits while you are using ergoloid mesylates. Your family or other caregivers should also be alert to changes in your mood or symptoms.

It may take up to 4 weeks before your symptoms improve. For best results, keep using the medication as directed.

Call your doctor if your symptoms do not improve after 3 weeks of treatment.

Store at room temperature away from moisture, heat, and light.

Ergoloid mesylates dosing information

Usual Adult Dose for Dementia:

1 mg orally 3 times a day

-The decision to treat an individual with an ill-defined decline in mental capacity may result in missing underlying conditions that could be reversible and treatable; great care should be exercised to exclude delirium secondary to systemic disease, primary neurological disease, or primary disturbance of mood as possible conditions prior to treatment.
-Continued clinical evaluation is necessary during treatment as the patient's condition may evolve sufficiently to allow for a specific diagnosis and specific alternative treatment.

Use: Symptomatic relief of an idiopathic decline in mental capacity effecting self-care, mood, motivation, cognitive and interpersonal skills.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking ergoloid mesylates?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect ergoloid mesylates?

Other drugs may interact with ergoloid mesylates, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.