Syndros Disease Interactions
There are 4 disease interactions with Syndros (dronabinol).
Dronabinol (applies to Syndros) seizures
Moderate Potential Hazard, Moderate plausibility.
Seizures and seizure- like activity have been reported in patients using dronabinol. Caution is advised in patients with history of a seizure disorder, as dronabinol may lower seizure threshold. Therapy should be discontinued immediately in patients who develop seizures and medical attention should be sought immediately.
Miscellaneous antiemetics (applies to Syndros) cardiac disease
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Cardiovascular Disease
The use of some antiemetics such as dronabinol and nabilone has been associated with occasional hypotension, possible hypertension, syncope or tachycardia. Therapy with these drugs should be administered cautiously in patients with cardiac disease.
Miscellaneous antiemetics (applies to Syndros) psychoses/depression
Moderate Potential Hazard, High plausibility. Applicable conditions: Psychosis
Some antiemetics such as dronabinol and nabilone may precipitate or exacerbate psychotic symptoms or anxiety, depression, hallucinations or psychosis. Therapy with these drugs should be administered cautiously in patients with a history of psychiatric disorders, emotional instability, or depression, and particularly if they are elderly. Careful psychiatric monitoring is advised.
Miscellaneous antiemetics (applies to Syndros) substance abuse
Moderate Potential Hazard, High plausibility. Applicable conditions: Drug Abuse/Dependence, Alcoholism
Some antiemetics as dronabinol and nabilone have a significant potential for abuse. Therapy with these drugs should be administered cautiously in patients with a history of substance abuse. It may be prudent to refrain from dispensing large quantities of dronabinol to these patients.
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Syndros drug interactions
There are 398 drug interactions with Syndros (dronabinol).
Syndros alcohol/food interactions
There is 1 alcohol/food interaction with Syndros (dronabinol).
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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