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Cubicin (daptomycin) Disease Interactions

There is 1 disease interaction with Cubicin (daptomycin):

Moderate

Daptomycin (Includes Cubicin) ↔ Renal Dysfunction

Moderate Potential Hazard, Moderate plausibility

Applies to: Renal Dysfunction

Renal function tests and CPK should be monitored frequently in patients with renal impairment that are in treatment with daptomycin. Additionally, the success rates of treatment with this drug were lower when used in patients with CrCl <50 mL/min. This should be taken into account when selecting an antibacterial therapy in patients with baseline moderate to severe renal impairment.

Cubicin (daptomycin) drug Interactions

There are 78 drug interactions with Cubicin (daptomycin)

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.

Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.

Do not stop taking any medications without consulting your healthcare provider.

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