Skip to main content

Lotrimin AF Athlete's Foot Cream Disease Interactions

There is 1 disease interaction with Lotrimin AF Athlete's Foot Cream (clotrimazole topical).


Clotrimazole lozenges (applies to Lotrimin AF Athlete's Foot Cream) liver impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

Abnormal liver function tests have been reported in patients treated with clotrimazole lozenges. Elevated SGOT levels were reported in about 15% of patients in clinical trials. Elevations were usually minimal and difficult to distinguish if caused by clotrimazole, other treatments or underlying disease. Periodic assessment of liver function is recommended, especially in patients with preexisting liver impairment.


  1. "Product Information. Mycelex (clotrimazole)." Bayer (2001):

Report options

Share by QR Code
QR code containing a link to this page

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.