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Bromfenac Disease Interactions

There are 3 disease interactions with bromfenac:


NSAIDs (Includes bromfenac) ↔ heart failure

Moderate Potential Hazard, Moderate plausibility. Applies to: Congestive Heart Failure

Fluid retention and edema have been observed in patients treated with NSAIDs, including some topical formulations. These drugs should be used with caution in patients with fluid retention or heart failure.


NSAIDs (Includes bromfenac) ↔ hyperkalemia

Moderate Potential Hazard, Moderate plausibility. Applies to: Hyperkalemia, Renal Dysfunction

Increase in serum potassium concentration, including hyperkalemia, have been reported with use of NSAIDs, even in some patients without renal impairment. In patients with normal renal function, these effects have been attributed to a hyporeninemic- hypoaldosteronism state.


NSAIDs (Includes bromfenac) ↔ hypertension

Moderate Potential Hazard, Moderate plausibility. Applies to: Hypertension

NSAIDs including topicals can lead to the onset of new hypertension or worsening of preexisting hypertension, either of which can contribute to the increased incidence of cardiovascular events. Blood pressure should be monitored closely during NSAID therapy and throughout the course of therapy.

Bromfenac drug interactions

There are 416 drug interactions with bromfenac

Bromfenac alcohol/food interactions

There are 2 alcohol/food interactions with bromfenac

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.