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Amphocin (amphotericin b) Disease Interactions

There is 1 disease interaction with Amphocin (amphotericin b):

Moderate

Ampho B (Includes Amphocin) ↔ anemia

Moderate Potential Hazard, High plausibility. Applies to: Anemia

Intravenous amphotericin B therapy may depress erythropoietin and red blood cell production and commonly causes a normocytic, normochromic anemia. Although the anemia is well tolerated by most patients and usually reverses completely within several months of stopping therapy, it may be problematic in patients with preexisting anemia. Intravenous therapy with amphotericin B should be administered cautiously in anemic patients or those predisposed to anemia. Frequent monitoring of blood counts and hemoglobin concentrations are recommended.

References

  1. Lyman C, Walsh T "Systemically administered antifungal agents." Drugs 44 (1992): 9-35
  2. "Amphotericin." Med Lett Drugs Ther 30 (1988): 30-2
  3. Miller R, Bates J "Amphotericin B toxicity." Ann Intern Med 71 (1969): 1089-95
  4. "Product Information. Fungizone (amphotericin B)." Bristol-Myers Squibb, Princeton, NJ.
  5. Struijk D, Krediet R, Boeschoten E, Rietra JG, Arisz L "Antifungal treatment of candida peritonitis in continuous ambulatory peritoneal dialysis patients." Am J Kidney Dis 9 (1987): 66-70
  6. Maddux M, Barriere S "A review of complications of amphotericin B therapy: recommendations for prevention and management." Drug Intell Clin Pharm 14 (1980): 177-81
  7. American Medical Association, Division of Drugs and Toxicology "Drug evaluations annual 1994." Chicago, IL: American Medical Association; (1994):
View all 7 references

Amphocin (amphotericin b) drug interactions

There are 221 drug interactions with Amphocin (amphotericin b)

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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