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Aloe polysaccharides/iodoquinol topical Disease Interactions

There are 4 disease interactions with aloe polysaccharides / iodoquinol topical.

Moderate

Iodoquinol topical (applies to aloe polysaccharides/iodoquinol topical) hepatic dysfunction

Moderate Potential Hazard, Low plausibility. Applicable conditions: Liver Disease

Percutaneous absorption of iodoquinol topical has not been characterized, however, other 8-hydroxyquinoline derivatives (clioquinol, chlorquinaldol) are systemically absorbed following topical application. The use of oral iodoquinol therapy is contraindicated in patients with hepatic disease.

Moderate

Iodoquinol topical (applies to aloe polysaccharides/iodoquinol topical) thyroid dysfunction

Moderate Potential Hazard, Low plausibility. Applicable conditions: Hypothyroidism, Hyperthyroidism

Percutaneous absorption of iodoquinol topical has not been characterized, however, other 8-hydroxyquinoline derivatives (clioquinol, chlorquinaldol) are systemically absorbed following topical application. The following thyroid abnormalities may occur during oral iodoquinol therapy: protein-bound serum iodine levels may be increased during treatment with iodoquinol resulting in alteration of certain thyroid function tests. Therapy with iodoquinol should be administered cautiously to patients with thyroid disease.

Moderate

Iodoquinol topical (applies to aloe polysaccharides/iodoquinol topical) visual field defects

Moderate Potential Hazard, Low plausibility. Applicable conditions: Visual Defect/Disturbance

Percutaneous absorption of iodoquinol topical has not been characterized. However, other 8-hydroxyquinoline derivatives (clioquinol, chlorquinaldol) are systemically absorbed following topical application. The following visual field defects have occurred during oral iodoquinol therapy: optic neuritis and optic atrophy when given in high dosages for prolonged periods. Optic atrophy has been reported mostly in children treated for acrodermatitis enteropathica at daily dosages between 1300 to 3600 mg for up to two years. Visual deterioration may be irreversible. Therapy with iodoquinol should be administered cautiously in patients with or predisposed to visual defects. Some clinicians also recommend not using iodoquinol and related agents in pediatric patients under 12 years of age. Long-term therapy should be avoided in all patients.

Moderate

Iodoquinol topical- peripheral neuropathy

Moderate Potential Hazard, Low plausibility.

Percutaneous absorption of iodoquinol topical has not been characterized, however, other 8-hydroxyquinoline derivatives (clioquinol, chlorquinaldol) are systemically absorbed following topical application. Peripheral neuropathies may occur during oral iodoquinol therapy. Therapy with iodoquinol topical should be administered cautiously in patients with peripheral neuropathy.

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Aloe polysaccharides/iodoquinol topical drug interactions

There is 1 drug interaction with aloe polysaccharides / iodoquinol topical.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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