Uroxatral (alfuzosin) Disease Interactions
There are 3 disease interactions with Uroxatral (alfuzosin):
Alfuzosin (Includes Uroxatral) ↔ hepatic impairment
Severe Potential Hazard, Moderate plausibility. Applies to: Liver Disease
Alfuzosin is contraindicated for use in patients with moderate or severe hepatic impairment (Child Pugh B and C). The pharmacokinetics of alfuzosin have not been studied in patients with mild hepatic impairment and caution should be exercised if it is administered to such patients.
Alfuzosin (Includes Uroxatral) ↔ renal impairment
Moderate Potential Hazard, Moderate plausibility. Applies to: Renal Dysfunction
Caution should be exercised when alfuzosin is administered in patients with severe renal impairment as safety data is limited on these patients (CrCl < 30 mL/min).
Antiadrenergic agents (Includes Uroxatral) ↔ cataracts
Moderate Potential Hazard, Moderate plausibility. Applies to: Cataracts
Intraoperative Floppy Iris Syndrome has been observed during cataract surgery in some patients on or previously treated with antiadrenergic agents. If a patient is undergoing cataract surgery, the ophthalmologist should be prepared for possible modifications of the surgical technique (iris hooks, iris dilator rings). There does not appear to be a benefit in stopping antiadrenergic agents therapy prior to the cataracts surgery.
Uroxatral (alfuzosin) drug interactions
There are 806 drug interactions with Uroxatral (alfuzosin)
Uroxatral (alfuzosin) alcohol/food interactions
There are 2 alcohol/food interactions with Uroxatral (alfuzosin)
More about Uroxatral (alfuzosin)
- Uroxatral Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Pricing & Coupons
- En Español
- 18 Reviews
- Generic Availability
- Drug class: antiadrenergic agents, peripherally acting
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
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