Medically reviewed on September 3, 2018
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
Uses For edaravone
Edaravone is used to treat patients with amyotrophic lateral sclerosis (ALS), which is also known as Lou Gehrig's disease.
Edaravone is available only with your doctor's prescription.
Before Using edaravone
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For edaravone, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to edaravone or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of edaravone in the pediatric population. Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of edaravone in the elderly.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of edaravone. Make sure you tell your doctor if you have any other medical problems, especially:
- Asthma, or history of or
- Sulfite allergy, history of—Edaravone contains sodium bisulfite which may cause an allergic reaction in patients with these conditions.
Proper Use of edaravone
A doctor or other trained health professional will give you edaravone. It is given through a needle placed in a vein.
Edaravone should come with a patient information leaflet. Read and follow the information carefully. Ask your doctor if you have any questions.
Precautions While Using edaravone
Your doctor will check your progress closely while you are receiving edaravone. This will allow your doctor to see if the medicine is working properly and to check for unwanted effects.
Edaravone may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and requires immediate medical attention. Talk to your nurse or doctor right away if you have very fast or irregular breathing, a very fast or irregular heartbeat, a rash, fainting, hive-like swellings on the skin, or swelling of the eyelids or around the eyes, face, lips, or tongue.
Edaravone Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
- Blistering, crusting, irritation, itching, or reddening of the skin
- blue lips, fingernails, or skin
- chest pain or tightness
- change in walking and balance
- clumsiness or unsteadiness
- cracked, dry, scaly skin
- difficult or troubled breathing
- fast heartbeat
- hives, itching, rash, or swelling
- irregular, fast or slow, or shallow breathing
- skin rash, encrusted, scaly and oozing
- unusual bruising
- Sugar in the urine
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- itching in genital or other skin areas
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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More about edaravone
- Edaravone Side Effects
- During Pregnancy
- Dosage Information
- En Español
- Drug class: miscellaneous central nervous system agents
Other brands: Radicava