diethylpropion (Oral route)Pronunciation
Commonly used brand name(s)
In the U.S.
- Tenuate Dospan
Available Dosage Forms:
- Tablet, Extended Release
Therapeutic Class: Appetite Suppressant, Centrally Acting
Chemical Class: Diethylpropion
Uses For diethylpropion
Diethylpropion is used as part of a short-term plan, along with a low calorie diet, for weight reduction. It is used in obese patients who have not been able to lose weight with diet and exercise alone. Diethylpropion belongs to the group of medicines known as appetite suppressants.
diethylpropion is available only with your doctor's prescription.
Before Using diethylpropion
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For diethylpropion, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to diethylpropion or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of diethylpropion in children younger than 17 years of age. Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of diethylpropion in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving diethylpropion.
|All Trimesters||B||Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.|
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking diethylpropion, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using diethylpropion with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of diethylpropion. Make sure you tell your doctor if you have any other medical problems, especially:
- Agitated state or
- Arteriosclerosis (hardening of the arteries), advanced or
- Drug abuse or dependence, history of or
- Glaucoma or
- Heart problems (e.g., heart murmur, valvular heart disease) or
- Hypertension (high blood pressure), severe or
- Hyperthyroidism (overactive thyroid) or
- Pulmonary hypertension (increased blood pressure in the lungs)—Should not be used in patients with these conditions.
- Heart or blood vessel disease or
- Heart rhythm problems (e.g., arrhythmia) or
- Hypertension (high blood pressure), mild to moderate or
- Mental illness or
- Seizures or epilepsy—Use with caution. May make these conditions worse.
- Kidney disease—Use with caution. Higher blood levels of diethylpropion can occur, which increases the risk of serious side effects.
Proper Use of diethylpropion
Take diethylpropion only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much is taken, it may become habit-forming (causing mental or physical dependence).
diethylpropion is available in two forms: the immediate-release tablets and the controlled-release tablets. Ask your doctor which dosage form is right for you.
Swallow the controlled-release tablets whole. Do not break, crush, or chew it.
Carefully follow your doctor's instructions for a reduced-calorie diet plan and regular exercise. Talk with your doctor before starting any exercise program.
The dose of diethylpropion will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of diethylpropion. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For treatment of obesity:
- For oral dosage form (immediate-release tablets):
- Adults and teenagers 17 years of age and older—25 milligrams (mg) three times a day, taken one hour before meals, and in mid evening to overcome night hunger.
- Children 16 years of age and younger—Use is not recommended.
- For oral dosage form (controlled-release tablets):
- Adults and teenagers 17 years of age and older—75 milligrams (mg) once a day, taken usually in mid morning.
- Children 16 years of age and younger—Use is not recommended.
- For oral dosage form (immediate-release tablets):
If you miss a dose of diethylpropion, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Precautions While Using diethylpropion
It is very important that your doctor check your progress at regular visits to make sure that diethylpropion is working properly and does not cause any unwanted effects.
Do not use diethylpropion if you are also using similar medicines such as benzphetamine, mazindol, phendimetrazine, phentermine, Bontril®, Didrex®, or Suprenza™. Also, do not use diethylpropion if you have used an MAO inhibitor (MAOI) such as Eldepryl®, Marplan®, Nardil®, or Parnate® within the past 14 days. Using these medicines together may cause serious unwanted effects.
diethylpropion may be habit-forming. If you think diethylpropion is not working properly after you have taken it for 4 weeks, do not increase the dose. Instead, check with your doctor.
Stop using diethylpropion and check with your doctor right away if you notice a decrease in your ability to exercise, if you faint, or if you have chest pain, swelling of your feet or lower legs, or trouble with breathing. These may be symptoms of a very serious heart or lung problem.
diethylpropion may cause some people to become dizzy, lightheaded, or less alert than they are normally. Make sure you know how you react to diethylpropion before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.
diethylpropion will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; medicine for seizures (such as barbiturates); muscle relaxants; or anesthetics, including some dental anesthetics. Check with your medical doctor or dentist before taking any of the above while you are taking diethylpropion.
For diabetic patients: diethylpropion may affect blood sugar levels. If you notice a change in the results of your blood or urine sugar tests or if you have any questions, check with your doctor.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription and nonprescription (over-the-counter) medicines, dietary supplements, herbal remedies, or medicines for appetite control, asthma, colds, cough, hay fever, and sinus problems.
diethylpropion Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:Rare
- Seeing, hearing, or feeling things that are not there
- severe mental changes
- shortness of breath
- Black, tarry stools
- blurred vision
- burning while urinating
- chest pain
- cough or hoarseness
- decreased ability to exercise
- difficult or labored breathing
- difficult or painful urination
- false or unusual sense of well-being
- fast, slow, pounding, or irregular heartbeat or pulse
- fear or nervousness
- fever with or without chills
- frequent urination
- general feeling of tiredness or weakness
- inability to speak
- increased volume of pale, dilute urine
- lower back or side pain
- numbness or tingling in the face, arms, or legs
- severe or sudden headache
- shakiness in the legs, arms, hands, or feet
- slurred speech
- sore throat
- sores, ulcers, or white spots on the lips or in the mouth
- swelling of the feet or lower legs
- swollen glands
- temporary blindness
- tightness in the chest
- trembling or shaking of the hands or feet
- trouble with breathing
- twitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
- unusual bleeding or bruising
- unusual tiredness or weakness
- vision problems
- weakness in the arm or leg on one side of the body, sudden and severe
Get emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdose
- Abdominal or stomach cramps
- bigger, dilated, or enlarged pupils (black part of the eye)
- change in consciousness
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- increased sensitivity of the eyes to light
- loss of consciousness
- overactive reflexes
- physical attempt to injure
- violent actions
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Incidence not known
- Abdominal or stomach discomfort
- difficulty having a bowel movement (stool)
- dry mouth
- general feeling of discomfort or illness
- hair loss
- hives or welts
- large, flat, blue, or purplish patches in the skin
- loss of appetite
- muscle pain
- passing of gas
- redness of the skin
- skin rash
- stomach fullness or discomfort
- trouble sleeping
- unable to sleep
- unpleasant taste
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
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