Antihemophilic factor (recombinant), glycopegylated-exei (Intravenous)
Generic name: antihemophilic factor (recombinant), glycopegylated-exei (an-tye-hee-moe-FIL-ik FAK-tor (re-KOM-bin-ant), glye-koe-PEG-il-ay-ted-exei)
Drug class: Miscellaneous coagulation modifiers
Medically reviewed by Drugs.com. Last updated on Jan 25, 2023.
Uses for antihemophilic factor (recombinant), glycopegylated-exei
Antihemophilic factor (recombinant), glycopegylated-exei injection is used to treat and control bleeding in patients with hemophilia A (congenital Factor VIII deficiency). It is also used to reduce the number of bleeding episodes in patients when used regularly. Antihemophilic factor (recombinant), glycopegylated-exei injection is also used to prevent bleeding during a surgical procedure.
This medicine is available only with your doctor's prescription.
Before using antihemophilic factor (recombinant), glycopegylated-exei
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of antihemophilic factor (recombinant), glycopegylated-exei injection in children. Safety and efficacy have been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of antihemophilic factor (recombinant), glycopegylated-exei injection in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Allergy to hamster proteins or
- von Willebrand disease (blood clotting disorder)—Should not be used in patients with these conditions.
Proper use of antihemophilic factor (recombinant), glycopegylated-exei
A doctor or other trained health professional will give you this medicine in a medical facility. You may also be trained to administer this medicine yourself. It is given through a needle placed into one of your veins.
Swirl the vial gently to dissolve the powder. Do not shake. Do not use the mixed liquid if it is cloudy, discolored, or has particles in it.
Inject the mixed liquid right away or you may store it in the refrigerator for not more than 24 hours or at room temperature for not more than 4 hours. Throw away any unused medicine after 4 hours if kept at room temperature or after 24 hours if refrigerated.
Precautions while using antihemophilic factor (recombinant), glycopegylated-exei
It is very important that your doctor check your or your child's progress closely while receiving this medicine to make sure it is working properly. Blood tests will be needed to check for unwanted effects.
Call your doctor right away if this medicine does not prevent or stop bleeding as expected.
This medicine may cause a serious allergic reaction, called anaphylaxis, which can be life-threatening and requires immediate medical attention. Tell your doctor right away if you or your child have a rash, itching, hoarseness, trouble breathing or swallowing, or any swelling of your hands, face, or mouth after using this medicine.
Side Effects of antihemophilic factor (recombinant), glycopegylated-exei
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Incidence not known
- Fast heartbeat
- hives, itching, skin rash
- joint pain, stiffness, or swelling
- redness of the skin
- swelling of the eyelids, face, lips, hands, or feet
- tightness in the chest
- troubled breathing or swallowing
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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