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Antihemophilic factor (recombinant), fc-vwf-xten fusion protein-ehtl (Intravenous)

Generic name: antihemophilic factor (recombinant), fc-vwf-xten fusion protein-ehtl (an-tee-hee-moe-FIL-ik FAK-tor (ree-KOM-bi-nant) Fc-VWF-XTEN FUE-zhun PROE-teen - ehtl)
Brand name: Altuviiio
Drug class: Miscellaneous coagulation modifiers

Medically reviewed by Drugs.com. Last updated on Oct 14, 2023.

Uses for antihemophilic factor (recombinant), fc-vwf-xten fusion protein-ehtl

Antihemophilic factor (recombinant), Fc-VWF-XTEN fusion protein-ehtl injection is used to treat, control, prevent, and decrease the frequency of bleeding episodes, and prevent bleeding during surgery in patients with hemophilia A (congenital Factor XIII deficiency).

This medicine is available only with your doctor's prescription.

Before using antihemophilic factor (recombinant), fc-vwf-xten fusion protein-ehtl

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of Altuviiio™ injection in children.

Geriatric

Appropriate studies have not been performed on the relationship of age to the effects of Altuviiio™ injection in geriatric patients.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper use of antihemophilic factor (recombinant), fc-vwf-xten fusion protein-ehtl

A nurse or other trained health professional will give you this medicine in a hospital or clinic. It is given through a needle placed into one of your veins. You may also be taught how to give this medicine at home.

This medicine comes with a patient information leaflet and instructions for use. Read and follow the instructions carefully. Ask your doctor if you have any questions.

To prepare the medicine using 1 vial and 1 prefilled syringe:

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Missed Dose

Call your doctor or pharmacist for instructions.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature or in the refrigerator, away from heat, moisture, and direct light. Keep from freezing. If stored at room temperature, the medicine will expire at 6 months or after the expiration date, whichever comes first.

Do not return the room temperature medicine in the refrigerator.

Use the mixture within 3 hours after it is prepared. Do not store in the refrigerator after mixing and use later.

Precautions while using antihemophilic factor (recombinant), fc-vwf-xten fusion protein-ehtl

It is very important that your doctor check your progress closely while you are receiving this medicine to make sure it is working properly. Blood tests are needed to check for unwanted effects.

This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention. Tell your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after you get the injection.

Side Effects of antihemophilic factor (recombinant), fc-vwf-xten fusion protein-ehtl

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Incidence not known

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Commonly used brand name(s)

In the U.S.

Available Dosage Forms:

Therapeutic Class: Antihemophilic Agent

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.