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Anthim (Intravenous)

Generic Name: obiltoxaximab (Intravenous route)

oh-bil-tox-AX-i-mab

Commonly used brand name(s)

In the U.S.

  • Anthim

Available Dosage Forms:

  • Solution

Pharmacologic Class: Monoclonal Antibody

Uses For Anthim

Obiltoxaximab injection is used together with antibiotics to treat inhalational anthrax. It is also used to prevent inhalational anthrax after a person is exposed. Obiltoxaximab works by preventing the anthrax bacteria from entering the body's cells, which prevents an infection.

This medicine is to be given only by or under the direct supervision of your doctor.

Before Using Anthim

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of obiltoxaximab injection in children.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of obiltoxaximab injection in the elderly.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of Anthim

A nurse or other trained health professional will give you this medicine. The medicine is given through a needle placed in a vein.

You may also receive medicines (eg, diphenhydramine, Benadryl®) before you receive obiltoxaximab to help prevent allergic reactions to the injection.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Precautions While Using Anthim

Your doctor will check your progress closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly and to check for unwanted effects.

This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Talk to your nurse or doctor right away if you have very fast or irregular breathing, a very fast or irregular heartbeat, a rash, fainting, hive-like swellings on the skin, or swelling of the eyelids or around the eyes, face, lips, or tongue.

Anthim Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common
  • Chest discomfort
  • cough
  • difficulty swallowing
  • dizziness
  • fainting or loss of consciousness
  • fast heartbeat
  • fast or irregular breathing
  • hives, itching, or skin rash
  • swelling of the eyelids or around the eyes, face, lips, or tongue
  • trouble breathing
  • unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Headache
Less common
  • Body aches or pain
  • chills
  • ear congestion
  • fever
  • loss of voice
  • nasal congestion
  • pain, bruise, or swelling at the injection site
  • pain in the arms or legs
  • runny nose
  • sneezing
  • sore throat
Less common or rare
  • Bone pain
  • difficulty with moving
  • dry mouth
  • muscle aching or cramping
  • muscle pains or stiffness
  • swollen joints

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

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