Comparing Zoloft vs Effexor
Zoloft | Effexor |
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Zoloft (sertraline) | Effexor (venlafaxine) |
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Prescription only
Zoloft is a brand name for sertraline which is an effective antidepressant with less potential for drowsiness than many other antidepressants. It belongs to the group of medicines called selective... View more |
Prescription only
Effexor is an antidepressant that may cause a discontinuation syndrome if abruptly stopped after long-term administration. Prescribed for Autism, Depression, Major Depressive Disorder, Bulimia... View more |
Related suggestions Depression
Major Depressive Disorder
Postpartum Depression
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More about Zoloft (sertraline) | More about (venlafaxine) | ||||||||
Ratings & Reviews | |||||||||
Zoloft has an average rating of 7.3 out of 10 from a total of 1948 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 19% reported a negative effect. |
Effexor has an average rating of 5.9 out of 10 from a total of 489 ratings on Drugs.com. 45% of reviewers reported a positive effect, while 32% reported a negative effect. |
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Drug Class | |||||||||
Side Effects | |||||||||
See also: Zoloft side effects in more detail. |
See also: Effexor side effects in more detail. |
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Generic Availability | |||||||||
Pricing and Coupons * Prices are without insurance | |||||||||
View all Zoloft prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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Dosage Forms Available | |||||||||
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N/A |
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Brand Names | |||||||||
N/A |
Other venlafaxine brands include: Effexor XR | ||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||
66 hours |
4 hours |
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CSA Schedule ** View glossary of terms | |||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||
A total of 670 drugs are known to interact with Zoloft:
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A total of 693 drugs are known to interact with Effexor:
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Alcohol/Food/Lifestyle Interactions | |||||||||
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Disease Interactions | |||||||||
First Approval Date | |||||||||
December 30, 1991 |
N/A |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||
N/A |
N/A |
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More Information | |||||||||
Patient resources | |||||||||
N/A |
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Professional Resources | |||||||||
Related Treatment Guide | |||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.