Comparing Topamax vs Lyrica
Topamax | Lyrica |
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Topamax (topiramate) | Lyrica (pregabalin) |
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Prescription only
Topamax may be prescribed either alone or in combination with other medications for the treatment of certain types of epilepsy, or it may be given for the prevention of migraine. Drowsiness is a... View more |
Prescription only
Lyrica can help relieve nerve pain and control seizures but it is likely to cause drowsiness. Prescribed for Neuropathic Pain, Fibromyalgia, Neuralgia, Postherpetic Neuralgia, Diabetic Peripheral... View more |
Related suggestions |
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More about Topamax (topiramate) | More about Lyrica (pregabalin) | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Topamax has an average rating of 6.1 out of 10 from a total of 642 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 30% reported a negative effect. |
Lyrica has an average rating of 6.4 out of 10 from a total of 918 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 27% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: Topamax side effects in more detail. |
See also: Lyrica side effects in more detail. |
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Generic Availability | |||||||||||||||||
Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Topamax prices |
View all Lyrica prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Other topiramate brands include: Eprontia, Qudexy XR, Trokendi XR | Other pregabalin brands include: Lyrica CR | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
56 hours |
6.3 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4. |
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Pregnancy Category | |||||||||||||||||
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 289 drugs are known to interact with Topamax:
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A total of 284 drugs are known to interact with Lyrica:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
December 24, 1996 |
December 30, 2004 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.