Comparing Sustiva vs Truvada

For HIV Infection: Was on it for years before I developed resistance to it. MUST be taken at night to minimize side effects. Bad depression, confusion, random crying spells, feeling helpless, suicidal thoughts (& no I've never had it prior or after I stopped this medication). It does get better as the med levels out but the first couple weeks are torture! In a grocery store I sat on the floor crying because 3 things on my list were on the same isle. I've never experienced anything like that in my life!

For HIV Infection: Started on Atripla but after 3 months the dizziness and nausea was too much to bear. Changed to trivada and reduced to 400 mg sustiva and the side effects disappeared. Only slight lightheaded which resolved during the day. Sustiva works but 600 mg is too much. 400 mg was found to work just as well and with less side effects. The only problem is having to take three pills at once as sustiva only comes in 200 mg tabs. Encore study shows reduced dosage works just as well.

For HIV Infection: After one year on Truvada in combination with Prezista and Norvir - the only listed side effect I may be suffering from is insomnia - and I think that has more to do with other factors than with Truvada (I take it at Noon). After hearing about possible side effects with HIV medicines- it is a pleasant surprise!

For HIV Infection: I have been on the combination of Truvada/Prezista/Norvir for over 2 years now. The side effects that cause me the most problems are the ones dealing with my kidneys! The Truvada has made my GFR go down to 30, very close to changing medicines at that point. But it has been working so well that we took a very close monitoring of my kidney function, and my GFR has stabilized around 55. Other than that the side effects have been minimal to none. Great medicine overall!