Comparing Plaquenil vs Rinvoq
| Plaquenil (hydroxychloroquine) | Rinvoq (upadacitinib) |
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| Plaquenil (hydroxychloroquine) | Rinvoq (upadacitinib) |
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Prescription only
Prescribed for Rheumatoid Arthritis, Lupus, Lyme Disease - Arthritis, Dermatomyositis, Malaria Prevention, Malaria. Plaquenil may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Crohn's Disease, Ankylosing Spondylitis, Atopic Dermatitis, Non-Radiographic Axial Spondyloarthritis, Polyarticular Juvenile Idiopathic Arthritis, Giant Cell Arteritis, Psoriatic... View more |
Related suggestions Rheumatoid Arthritis
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| More about Plaquenil (hydroxychloroquine) | More about Rinvoq (upadacitinib) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Plaquenil has an average rating of 6.4 out of 10 from a total of 158 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 28% reported a negative effect. |
Rinvoq has an average rating of 7.0 out of 10 from a total of 225 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 17% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Plaquenil side effects |
View all Rinvoq side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Plaquenil prices |
View all Rinvoq prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other hydroxychloroquine brands include: Sovuna | Other upadacitinib brands include: Rinvoq LQ | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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N/A |
14 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 583 drugs are known to interact with Plaquenil:
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A total of 600 drugs are known to interact with Rinvoq:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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April 18, 1955 |
August 16, 2019 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.