Comparing Phenytoin vs Depakote
Phenytoin | Depakote |
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Phenytoin | Depakote (divalproex sodium) |
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Prescription only
Prescribed for Epilepsy, Seizures, Anxiety, Neurosurgery, Cluster-Tic Syndrome, Seizure Prophylaxis During or Following Neurosurgery, Status Epilepticus, Arrhythmia, Myotonia Congenita, Peripheral... View more |
Prescription only
Depakote may be used in the treatment of epilepsy and mania, and to prevent migraines; however, people taking Depakote should be monitored for potentially fatal side effects such as liver failure... View more |
Related suggestions Popular comparisons
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More about Phenytoin | More about Depakote (divalproex sodium) | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Phenytoin has an average rating of 7.5 out of 10 from a total of 112 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 17% reported a negative effect. |
Depakote has an average rating of 6.3 out of 10 from a total of 325 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 27% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: phenytoin side effects in more detail. |
See also: Depakote side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all phenytoin prices |
View all Depakote prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Di-Phen, Dilantin, Phenytek, Phenytoin Sodium, Phenytoin Sodium, Extended Release | Other divalproex sodium brands include: Depakote ER, Depakote Sprinkles | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
15 hours |
16 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
When Treating Epilepsy And Manic Episodes Associated With Bipolar Disorder
Category X
Not for use in pregnancy
When Treating Migraine See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 839 drugs are known to interact with phenytoin:
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A total of 409 drugs are known to interact with Depakote:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
January 06, 1953 |
March 10, 1983 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.