Comparing Nexlizet vs Simvastatin
| Nexlizet (bempedoic acid/ezetimibe) | Simvastatin |
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| Nexlizet (bempedoic acid/ezetimibe) | Simvastatin |
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Prescription only
Nexlizet contains ezetimibe and bempedoic acid and has been shown to decrease LDL-C levels by more than either drug alone. It is usually given in combination with other cholesterol-lowering... View more |
Prescription only
Simvastatin is effective at lowering cholesterol; however, it may cause muscle pain, particularly at higher dosages. Should not be used by people with active liver disease or in women planning a... View more |
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Popular comparisons
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| More about Nexlizet (bempedoic acid/ezetimibe) | More about Simvastatin | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Nexlizet has an average rating of 9.3 out of 10 from a total of 14 ratings on Drugs.com. 86% of reviewers reported a positive effect, while 0% reported a negative effect. |
Simvastatin has an average rating of 4.8 out of 10 from a total of 131 ratings on Drugs.com. 30% of reviewers reported a positive effect, while 48% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Nexlizet side effects |
View all Simvastatin side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Nexlizet prices |
View all Simvastatin prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
FloLipid, Zocor | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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22 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 110 drugs are known to interact with Nexlizet:
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A total of 335 drugs are known to interact with Simvastatin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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February 26, 2020 |
December 23, 1991 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.