Mitoxantrone Alternatives Compared
| Mitoxantrone | Methotrexate | Tabloid |
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| Mitoxantrone | Methotrexate | Tabloid thioguanine |
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Prescribed for Multiple Sclerosis, Prostate Cancer, Acute Nonlymphocytic Leukemia, Non-Hodgkin's Lymphoma. May also be prescribed off label for Mantle Cell Lymphoma. |
Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and... View more |
Prescribed for Acute Nonlymphocytic Leukemia. Tabloid may also be used for purposes not listed in this medication guide. |
Choose a suggestion below Acute Nonlymphocytic Leukemia
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| More about Mitoxantrone | More about Methotrexate | More about Tabloid (thioguanine) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
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No lower-cost generic available |
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| Availability | ||||||||||||||||||||||||||
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Prescription only |
Prescription only |
Prescription only |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Mitoxantrone has an average rating of 10.0 out of 10 from a total of 1 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
Methotrexate has an average rating of 6.6 out of 10 from a total of 264 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 24% reported a negative effect. |
Be the first to share your experience with this drug. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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Commonly reported side effects include: infection, upper respiratory tract infection, urinary tract infection, fungal infection, fungal skin infection, sepsis, alopecia, amenorrhea, cardiac arrhythmia, constipation, diarrhea, ecg abnormality, gastrointestinal hemorrhage, increased gamma-glutamyl transferase, leukopenia, menstrual disease, nausea, stomatitis, urine abnormality, abdominal pain, aphthous stomatitis, asthenia, burning sensation of gastrointestinal tract, cough, decreased hemoglobin, decreased white blood cell count, dyspnea, edema, epigastric pain, fatigue, fever, hematuria, hyperglycemia, hypocalcemia, hypokalemia, increased serum glucose, lymphocytopenia, mucositis, pharyngitis, rhinitis, stomach pain, thrombocytopenia, vomiting, weight gain, abnormal absolute neutrophil count, anorexia, malaise, nail bed changes. See the full mitoxantrone side effects document. |
Commonly reported side effects include: increased liver enzymes. See the full methotrexate side effects document. |
See the full Tabloid side effects document. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all mitoxantrone prices |
View all methotrexate prices |
View all Tabloid prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
Methotrexate LPF Sodium, Otrexup, Rasuvo, RediTrex, Trexall, Xatmep |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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37 hours |
15 hours |
11 hours |
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| CSA Schedule** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
Category X
Not for use in pregnancy
See the full Pregnancy Warnings document. |
Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 289 drugs are known to interact with mitoxantrone:
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A total of 625 drugs are known to interact with methotrexate:
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A total of 451 drugs are known to interact with Tabloid:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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N/A |
December 07, 1953 |
N/A |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.