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Comparing Leucovorin vs Levoleucovorin

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Leucovorin Remove Leucovorin from your drug comparison Levoleucovorin Remove Levoleucovorin from your drug comparison
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Leucovorin Remove Leucovorin from your drug comparison Levoleucovorin Remove Levoleucovorin from your drug comparison

Prescribed for Methotrexate Overdosage, Colorectal Cancer, Folic Acid Antagonist Overdose, Anemia - Megaloblastic, Methotrexate Rescue, Pneumocystis Pneumonia, Pneumocystis Pneumonia Prophylaxis,... View more

Prescribed for Colorectal Cancer, Methotrexate Overdosage, Methotrexate Rescue. levoleucovorin may also be used for purposes not listed in this medication guide.

Prescription only

Prescription only

Ratings & Reviews

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Drug Class

Side Effects

See the full leucovorin side effects document.

See the full levoleucovorin side effects document.

Pricing and Coupons

* Prices are without insurance
Quantity 30 tablet
Dosage 5 mg
Per Unit* $1.09
Cost* $32.79

View all leucovorin prices

Quantity 17.5 mL
Dosage 10 mg/mL
Per Unit* $5.82 - $40.44
Cost* $101.90 - $707.75

View all levoleucovorin prices

Get free Discount Card

Get free Discount Card

Generic Availability

Yes (this medicine)

Yes (this medicine)

Dosage Form(s) Available
  • Injectable powder for injection
  • Injectable solution
  • Oral tablet
  • Intravenous powder for injection
  • Intravenous solution

Brand Names
Wellcovorin Fusilev, Khapzory

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

1 hour

6.8 hours

CSA Schedule**

View glossary of terms.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category
C
Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.
C
Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

FDA Alerts

FDA Alerts (1)

FDA Alerts (1)

Drug Interactions

A total of 27 drugs are known to interact with leucovorin:

  • 4 major drug interactions (10 brand and generic names)
  • 22 moderate drug interactions (140 brand and generic names)
  • 1 minor drug interactions (4 brand and generic names)

A total of 24 drugs are known to interact with levoleucovorin:

  • 4 major drug interactions (10 brand and generic names)
  • 20 moderate drug interactions (69 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease Interactions

First Approval Date

February 08, 1980

N/A

WADA Class

View World Anti-Doping Agency classifications.

N/A

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer