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Comparing Carbidopa / Levodopa vs Neupro

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Carbidopa / levodopa Neupro (rotigotine)
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Carbidopa / levodopa Neupro (rotigotine)
Prescription only

Carbidopa/levodopa is a medication that may be used for the treatment of Parkinson's disease. Available as immediate-release tablets, extended-release tablets, and extended-release capsules... View more

Prescription only

Prescribed for Restless Legs Syndrome, Parkinson's Disease. Neupro may also be used for purposes not listed in this medication guide.

More about Carbidopa / levodopa More about Neupro (rotigotine)
Ratings & Reviews

Carbidopa / levodopa has an average rating of 7.2 out of 10 from a total of 94 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 20% reported a negative effect.

Neupro has an average rating of 7.6 out of 10 from a total of 73 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 12% reported a negative effect.

View all 94 reviews

View all 73 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Carbidopa / levodopa side effects

View all Neupro side effects
Drug Class
Generic Availability

Lower cost generic

No lower cost generic approved
Pricing and Coupons * Prices are without insurance
Quantity 100 each
Strength 25 mg-100 mg
Per unit* $0.31 - $0.67
Cost* $31.01 - $67.40

View all Carbidopa / levodopa prices

Quantity 30 film, extended release
Strength 1 mg/24 hr
Per unit* $31.08
Cost* $932.29

View all Neupro prices

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Dosage Forms
  • Oral tablet
  • Oral tablet, disintegrating
  • Oral tablet, extended release
  • Transdermal film, extended release
Brand Names
Atamet, Crexont, Dhivy, Duopa, Parcopa, Rytary, Sinemet

N/A
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

2.3 hours

7 hours
CSA Schedule 1 View glossary of CSA terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.
Drug Interactions

A total of 520 drugs are known to interact with Carbidopa / levodopa:

  • 50 major drug interactions (158 brand and generic names)
  • 459 moderate drug interactions (3235 brand and generic names)
  • 11 minor drug interactions (111 brand and generic names)

A total of 256 drugs are known to interact with Neupro:

  • 40 major drug interactions (135 brand and generic names)
  • 215 moderate drug interactions (1042 brand and generic names)
  • 1 minor drug interactions (3 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • Alcohol can increase the nervous system side effects of levodopa such as dizziness, drowsiness, and... View more
  • Alcohol can increase the nervous system side effects of rotigotine such as dizziness, drowsiness... View more
Disease Interactions
First Approval Date

May 02, 1975

May 09, 2007
WADA Class View classifications

N/A

N/A
More Information
Patient Resources
Professional Resources
Related Treatment Guide

1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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