Comparing Caffeine vs Modafinil
| Caffeine | Modafinil |
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| Caffeine | Modafinil |
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Prescription and OTC
Prescribed for Drowsiness, Asthma, Apnea of Prematurity. Caffeine may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Chronic Fatigue Syndrome, ADHD, Depression, Fatigue, Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, Shift Work Sleep Disorder, Idiopathic Hypersomnia. Modafinil may also be... View more |
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| More about Caffeine | More about Modafinil | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Caffeine has an average rating of 6.7 out of 10 from a total of 39 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 28% reported a negative effect. |
Modafinil has an average rating of 7.3 out of 10 from a total of 536 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Caffeine side effects |
View all Modafinil side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Caffeine prices |
View all Modafinil prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| 357 HR Magnum, Alert, Cafcit, Caffedrine, ConRx Alert, Diurex Maximum Relief Water Caps, Diurex Ultra, Enerjets, Fastlene, Jet Alert Double Strength, Jet Alert Maximum Strength, Jet Alert Regular Strength, Keep Going, Molie, NoDoz, Overtime, Pep-Back ReCharge, Pep-Back Ultra, Stay Awake, Valentine, Vivarin View more | Provigil | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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4 hours |
15 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
Caffeine Citrate Injection
Category N
Not classified
Excluding Caffeine Citrate Injection See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 110 drugs are known to interact with Caffeine:
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A total of 522 drugs are known to interact with Modafinil:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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September 21, 1999 |
December 24, 1998 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.