Comparing Acetaminophen / Hydrocodone vs Promethazine DM
Acetaminophen / hydrocodone | Promethazine DM |
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Acetaminophen / hydrocodone | Promethazine DM (dextromethorphan / promethazine) |
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Prescription only
Acetaminophen/hydrocodone may be used to treat moderate-to-severe pain that is unrelieved by nonopioid analgesics. However, its use is limited by the dependence and addiction potential of the... View more |
Prescription only
Prescribed for Cough, Allergic Rhinitis, Cold Symptoms. Promethazine DM may also be used for purposes not listed in this medication guide. |
Related suggestions |
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More about Acetaminophen / hydrocodone | More about Promethazine DM (dextromethorphan / promethazine) | ||||||||
Ratings & Reviews | |||||||||
Acetaminophen / hydrocodone has an average rating of 6.0 out of 10 from a total of 1314 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 35% reported a negative effect. |
Promethazine DM has an average rating of 5.5 out of 10 from a total of 40 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 44% reported a negative effect. |
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Drug Class | |||||||||
Side Effects | |||||||||
See also: acetaminophen / hydrocodone side effects in more detail. |
See also: Promethazine DM side effects in more detail. |
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Generic Availability | |||||||||
Lower cost generic |
N/A |
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Pricing and Coupons * Prices are without insurance | |||||||||
View all acetaminophen / hydrocodone prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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Dosage Forms Available | |||||||||
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Brand Names | |||||||||
Xodol, Zyfrel |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||
3.8 hours |
16 hours |
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CSA Schedule ** View glossary of terms | |||||||||
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||
A total of 645 drugs are known to interact with acetaminophen / hydrocodone:
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A total of 730 drugs are known to interact with Promethazine DM:
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Alcohol/Food/Lifestyle Interactions | |||||||||
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Disease Interactions | |||||||||
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First Approval Date | |||||||||
May 03, 1982 |
February 14, 2006 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||
N/A |
N/A |
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More Information | |||||||||
Patient resources | |||||||||
Professional Resources | |||||||||
Related Treatment Guide | |||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.