Skip to Content

User Reviews for Tryptophan

Also known as: Aminomine

Tryptophan has an average rating of 6.8 out of 10 from a total of 12 ratings on Drugs.com. 64% of those users who reviewed Tryptophan reported a positive effect, while 36% reported a negative effect.

Condition Avg. Rating Reviews Compare
Insomnia  Off-label
8.4
6 reviews 106 medications
Depression  Off-label
3.5
4 reviews 78 medications
Anxiety  Off-label
9.0
1 reviews 53 medications
Premenstrual Dysphoric Disorder  Off-label
10.0
1 reviews 50 medications
Summary of Tryptophan reviews 6.8 12 reviews

Reviews may be moderated or edited before publication to correct grammar and spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest in the medication will not be published. As reviews and ratings are subjective and self-reported, this information should not be used as the basis for any statistical analysis or scientific studies.

Reviews for Tryptophan

Kieran · Taken for 6 months to 1 year July 31, 2020

For Depression: “I have tried L-tryptophan for months now, no effect. I have mild depression, with low serotonin as found in my tests.”

1 / 10
Was this helpful?YesNo
tj · Taken for less than 1 month January 23, 2020

For Insomnia: “I tried it for two nights, an hour before sleep for maintenance insomnia. Both times it made my sleep worse and far more alert than usual, definitely didn’t work for me.”

3 / 10
Was this helpful?YesNo
JJ · Taken for less than 1 month November 19, 2019

For Depression: “I began taking Tryptophan for low to moderate anxiety and depression, after having several failures with SSRI drugs. Started with 250mg, only two days... first day it made me feel much more relaxed... 2nd day it brought on anxiety attacks... I am still waiting for this stuff to get out of my system.”

3 / 10
Was this helpful?YesNo
JJ · Taken for less than 1 month November 17, 2019

For Anxiety: “After trying several SSRI drugs for my low to moderate anxiety and depression... I finally tried Tryptophan. I started with 250mg, a very low dose. IMHO, I think that many people start most drugs and alternative "remedies" at WAY too high a dosage... especially SSRIs, statins and tranqs. I slept well the first night, and woke feeling rested, and without the "cloud" of low-level anxiety and depression... I do NOT believe this was a "placebo" effect. I increased to 500mg, and slept and felt even better! I will stay at this dosage. Those with much more serious anxiety/depression may do better on a higher dose... but I strongly recommend moving up incrementally. I am still looking into what would be the best schedule for this... daily an hour before bedtime... or every other day... but this, for me... is a BIG winner!”

9 / 10
Was this helpful?YesNo
Anonymous February 20, 2012

For Insomnia: “I am a survivor of brain cancer and now have a memory deficit as a result. My Neurologist suggested I take 100mgs of L-Tryptophan daily to increase the production of serotonin. This he felt would assist with memory function. Long story short, 2 years later, I realize that I have benefited from the side effect of sleepiness. I take my 1000 mg before I go to bed and I sleep like a log.”

10 / 10
Was this helpful?YesNo
Coley T September 12, 2015

For Insomnia: “This seems to make me feel sleepy, and sleep better than the meds that the doctors have tried. I also like that I don't wake up feeling dopey and have that "hung over" feeling all day long that you get from some prescription meds.”

9 / 10
Was this helpful?YesNo
Anonymous · Taken for 1 to 6 months April 30, 2017

For Insomnia: “L-trytophan feels like a bit of a lifesaver for me. Having endured insomnia for 7 years and tried so many various treatments - this natural amino acid has given me back my energy and ability to sleep 7-8 hours just like other people do! The extras are that my mood is stable during pms and going through peri menopause. I feel happier, more relaxed and able to enjoy and appreciate my life so much more.”

10 / 10
Was this helpful?YesNo
Anonymous June 18, 2011

“I suffered through a year of acute insomnia triggered by strange noises coming from my sinus, probably some kind of twisted blood vessel although my ENT could never say for sure and I didn't want a CT scan. My MD had me on Zopiclone which is OK for short term but just garbage as far as long term use: it interferes with REM sleep, develops resistance and is hell to come off of with rebound insomnia and mood shifts, mostly dark. My MD was reluctant but I talked him into letting me try tryptohan. Ahh, sleeeep! Quality sleep too. Natural sleep. No side effects except the occasional morning headache and groggies that would soon disappear. No other side effects. No buidling up resistance over long term use. To me its been a sanity saver.”

Was this helpful?YesNo
Ally3 · Taken for 1 to 6 months February 18, 2017

For Depression: “I used this product and it rearly killed me.. is extremely dangerous combined with other medications and was banned for a reason. Now left with severe inflammation and nerve damage. Wish I'd researched further not just product reviews which are only positive. Please please ask your Dr first or research. Wish I had....”

1 / 10
Was this helpful?YesNo
Anonymous · Taken for 6 months to 1 year April 28, 2015

For Premenstrual Dysphoric Disorder: “Nothing, and I mean nothing (and I have tried everything) has helped my PMDD like L-Tryptophan has. My symptoms are now negligible with just one 500mg tablet plus a vitamin B supplement, once or at most twice a day.”

10 / 10
Was this helpful?YesNo
Shaun36 October 15, 2017

For Insomnia: “Used this for insomnia. I got no worthwhile results on the first night taking half hour before bed. The second night took one gave me a very gassy burps with a sort of grass like after taste. The third night took about 3 hours before bed this time about half an hour after taking I get another gassy burp but this time I involuntarily spit out this green grass looking stuff and just generally a very unpleasant taste in my mouth. Then five minutes later after a bit of water to get rid of the taste the roof of my mouth has that nasty stinging sensation like when a cold or flu bug is starting to kick in. horrible sensation yuck! Gonna chuck the rest of these in the bin!”

Was this helpful?YesNo
Anonymous March 25, 2011

For Insomnia: “L-Tryptophan has worked wonders for my insomnia, PMS, anxiety and depression. No side effects, although the bottle sayS take 3 capsules, I ONLY take 1 at night and wake up feeling great.”

10 / 10
Was this helpful?YesNo
ghjfd January 4, 2017

For Depression: “This helped me a lot, I feel more relaxed and motivated. When taking it before bed, sleep is very restful. No side effects”

9 / 10
Was this helpful?YesNo

This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.