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Tadalafil and Headaches: What Users Say

Brand names: Cialis, Adcirca, Tadliq, Chewtadzy, Alyq

Headaches: mentioned by 111 users (14.2%)

Based on user experiences from 782 Tadalafil reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

headaches 14.2%
back pain 6.5%
pain 3.5%
flushing 2.8%
runny nose 2.8%
stuffy nose 1.8%
heartburn 1.7%
dizziness 0.9%
erectile dysfunction 0.9%
muscle pain 0.9%

Reviews for Tadalafil

Commonly mentioned side effects
  • Bot...
  • Taken for less than 1 month
  • February 20, 2025

Tadalafil for Erectile Dysfunction "I've just crossed into my 60s and found that I was struggling to gain a strong erection and hold it; I've also been diagnosed with BPH and was taking 0.4 mg Tamsulosin daily in an effort to reduce frequent bathroom trips. After consulting with our family doctor, she recommended I stop the Tamsulosin and go with 5 mg Cialis daily. I followed her advice and started taking Cialis. My experience: for the first week, mild headaches (not requiring any painkillers) and towards the end of the week started experiencing lower back pain and joint aches. It got worse in the second week and although my pain tolerance is quite high, I found myself taking some painkillers to take the edge off as I really slowed down due to the discomfort. By the end of the second week, the headaches, back pain, and joint pain had all gone and my erections reminded me of my 20s and 30s. My wife and I couldn't be happier.. I would strongly recommend Cialis."

10 / 10
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9 Report
  • Old...
  • Taken for 1 to 2 years
  • February 17, 2025

Tadalafil for Erectile Dysfunction "Well, I’ve been taking this drug, on and off, for about two years now. I am in my mid-50s, and this drug has been doing wonders for me. I have mild erectile dysfunction. This just gave me the boost I needed. I take 5mg when needed. Within two hours, I am ready to go with my wife. Every time I’ve used this, my wife is like, 'Whoa, you took your pill.' The pill is satisfying for me and definitely for her as well. For me, the effects of the pill last about 24 hours, maybe a little more. So I can wake up in the morning and be ready again. If my wife is not in the mood early in the morning, I still wake up with a raging erection and have an amazing masturbation session. The only side effect is the occasional mild to moderate headache the next day. No worries, the good effects far outweigh the side effects."

10 / 10
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  • ass...
  • Taken for less than 1 month
  • December 20, 2024

Tadalafil for Erectile Dysfunction "I am a healthy male in my 30s, married. I'm a very busy husband and a father. I have a lot of stress and responsibility on my plate from my career and being tired from demanding responsibilities. I usually get an erection easily. But when I get intimate with my wife, after a few minutes, I lose hardness and my penis goes 50% limp, and if I don't get stimulated or reassured, then it goes 80% limp, ending in interruption or postponing it till another time. It caused a lot of frustration for me, e.g., self-esteem, confidence. Sex is one of the most important aspects of my relationship. I got Cialis 20 mg. It made me feel semi-aroused through the day and night, thinking about sex, feeling tingly, warm, and plump in the glans, sensual, even rubbing against my underwear my penis would ache, yearning for a good bj. I ejaculated 6 times in 36 hours. Mild headache and stuffy nose. The downside is the pill lasts a long time-can be a distracting feeling horny all day."

7 / 10
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4 Report

Frequently asked questions

  • ALH...
  • Taken for 1 to 2 years
  • November 28, 2024

For Erectile Dysfunction "I have used both Viagra and Tadalafil over a period of several years and must say that, in my opinion, Tadalafil is a far superior product to Viagra... with absolutely no side effects, unlike Viagra, which gave me blurry vision and slight headaches each morning, similar to a hangover... the daily option with Tadalafil is also very good... I am an older man and the daily option is also good... bringing back memories of my youth... ever ready... ps if you have benign prostate enlargement, it is also a treatment for this (unlike Viagra)... I would score 10/10 for Tadalafil... and 3/10 for Viagra."

10 / 10
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1 Report
  • Con...
  • Taken for 1 to 6 months
  • November 24, 2024

For Erectile Dysfunction "Used to take 5 mg daily with some benefit for both ED and BPH. Now taking Alfuzosin 10 mg daily and Tadalafil 20 mg twice weekly for symptoms. Erections and ejaculations are so much better with the higher dose. BPH symptoms also much improved. Some headaches initially from Tadalafil, but these faded away once my body became used to the drugs/higher dosage. Taking plenty of water to ensure good hydration helps minimize any side effects."

10 / 10
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  • dar...
  • Taken for 1 to 6 months
  • March 18, 2023

For Erectile Dysfunction "I've used the brand name Cialis and it has worked great, but this generic brand tadalafil from Ajanta Pharma USA Inc doesn't work. With the brand name Cialis, I would get an erection and a mild headache. I'm at 25 mg with this Ajanta Pharma and getting no response. So I'm stuck with 90 pills of this Ajanta Pharma brand."

1 / 10
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2 Report
  • cla...
  • Taken for 2 to 5 years
  • December 26, 2022

For Pulmonary Arterial Hypertension "My dad and I take tadalafil 1.25 mg daily for ED with no adverse events. I once took 5 mg, and then I had 99/66 arterial tension readings after a few hours; even after drinking a lot of liquids and a lot of coffee, they did not help raise these values. I had a severe headache as well, and 400 mg ibuprofen helped. My grandmother takes 2.5 mg tadalafil daily for hypertension with 50 mg metoprolol every 12 hours and 1.5 mg indapamide extended release daily. Her readings are 127/67 now. Amazing drug. She tried lisinopril, valsartan, and amlodipine before tadalafil. All had severe adverse reactions compared to tadalafil, especially amlodipine. She is also taking 300 mg allopurinol daily, 100 mg tramadol extended release every 12 hours, and 2.5 mg solifenacin daily. I have no idea whether these drugs also decrease arterial tension or not. She seems so happy."

10 / 10
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  • DMa...
  • Taken for 1 to 2 years
  • October 11, 2022

For Erectile Dysfunction "After reading the reviews on this site, I approached my physician for the prescription and chose the 5 mg daily strategy. You will always be ready when using this strategy. But as a boost, when you know you're gonna need to deliver the goods for a sustained amount of time, I take two extra 5 mg for a total of 15 mg. You will be solid and at attention no matter how many rounds you require. Plus, at full solid girth, your companion will be amazed. And you can deliver a huge payload if your companion is into that. I do experience a minor headache at 15 mg, but nothing in comparison to the experience. My companion rode it for 30 minutes and then came back for a second round. I'm 57 and feel like I'm in my early 20s again. Highly recommend the sustained level with a boost when needed!"

10 / 10
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10 Report
  • And...
  • Taken for 1 to 6 months
  • September 4, 2022

Tadalafil for Erectile Dysfunction "I’m 55 years old and have been noticing over 6 months a gradual decline with loss of firmness before and during sex. My penis became softer and less sensitive. I’m on beta blockers (Inderal), which helps me with social anxiety and high blood pressure. After researching possible causes, I put it down to age and possibly Inderal. I spoke to my doctor about the symptoms I was experiencing, and he prescribed 5 mg of Cialis daily. This has changed my life. After initially experiencing slight lower back pain, flushed face, and slight headaches, which all went away on day three, I’m now able to have sex with my girlfriend any time, night or day. I wake up with regular morning woods and experience thought-initiated erections throughout my day. During sex, my penis is more sensitive and remains rock hard and fully erect right up until I ejaculate. Within 10 minutes, I’m ready for round two. Speak to your doctor, this will change your life."

10 / 10
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25 Report
  • Anonymous
  • August 14, 2022

Tadalafil for Erectile Dysfunction "Not worth it. The headache and discomfort after are unbearable."

1 / 10
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4 Report
  • Anonymous
  • Taken for less than 1 month
  • April 22, 2022

Tadalafil for Erectile Dysfunction "Never use Cialis. It is better to die than suffer from the worst headache of life. It is life-threatening. It is definitely not for human beings."

1 / 10
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3 Report
  • Pet...
  • Taken for 1 to 2 years
  • February 8, 2022

For Erectile Dysfunction "Received an online prescription after consultation for 5 mg tadalafil. Took it at 6 pm, woke up with a rock-hard morning cock, edged and masturbated to a huge amount for about an hour. After about another hour and a half, my wife and I got intimate, and wow, with a little bit of stimulation I was rock-hard again! My wife commented on the fullness, thickness, and stiffness of my cock and could not keep her hands and mouth off of it. The effects lasted for about a day and a half, slight hot flushes in the face and slight headache, but no big deal. Extremely happy and will definitely continue with this medication!"

9 / 10
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3 Report
  • Ren...
  • Taken for 1 to 2 years
  • February 6, 2022

For Erectile Dysfunction "Have been using 1x10mg + 1x5mg, so a total of 15mg every other day for the last few weeks. Works really well for me. Have previously tried 5mg daily, but just doesn’t do enough for me. The first time I tried it, I had aching legs, some backache, and also a slight headache, but now no side effects at all. Overall, very satisfied."

9 / 10
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3 Report
  • Dav...
  • Taken for 1 to 6 months
  • January 28, 2022

Tadalafil for Erectile Dysfunction "I'm in my late forties, and for the last year, I have been suffering from depression. This made it very difficult for me to get an erection with my partner, and performance anxiety set in. I was stuck in a vicious circle, and things went from bad to worse. After a lot of research, I decided to try Cialis 10 mg. Wow... life-changing. With even just a little arousal, I was hard and stayed hard, and 5 minutes after orgasm, I was ready to go again and rock solid. I felt 20 years old again, and the effects seemed to last at least 48 hours. No bad side effects, but I did have a very slight headache, which was to me a very little price to pay. My sexual confidence is back, and I feel so much better."

10 / 10
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11 Report
  • Jac...
  • January 12, 2022

Tadalafil for Erectile Dysfunction "27-year-old male. Cialis has my blessing! I tried both Viagra and Cialis for performance anxiety-induced ED when I was seeing this really hot 20-year-old girl last summer after not being intimate with anybody for a long time. The first few times we tried to have sex, I couldn’t get erect or only partially erect, and although she was very sweet and understanding, the embarrassment I felt was unbearable. Both drugs were lifesavers and great in their own way. However, if I took Viagra, I would feel the need to get down to business ASAP after taking it and felt I would need to time when I took it properly, which would add to the anxiety. It also gave me horrible headaches. With Cialis, I could relax, cuddle, and take my time. I was able to do it when I was ready and didn’t have any side effects."

10 / 10
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24 Report
  • Hol...
  • Taken for 1 to 6 months
  • December 5, 2021

Tadalafil for Erectile Dysfunction "I'm 42 and a heavy weekend drinker that is overweight. I have a smoking-hot fiancée. In the past two years, I've had a problem keeping it up. I can get there but not keep it till she finishes. I could climax at half-staff, but if I wasn't hitting her deep spot, she wasn't going to get hers. So I ain't too proud to beg. I've had a urologist that I've liked since I was 39 because of stricture disease. I asked him what he thought was a good fit for me between the BIG 3 pills, and he said Cialis. I don't like Viagra, it's literally a splitting headache, and I cannot ejaculate. Levitra, on the other hand, was the SHOW! But only for a few hours. Doc prescribed me 20 mg Cialis, and holy guacamole! Man, this thing is a freight train! I'm sensitive, hard anytime, pop up outta nowhere like a high school boy. I literally had to call my girl and make her get home from the grocery store because I didn't know what to do with this thing! Morning wood a plenty also! 20 mg is a 2-3 day-er for me! Awesome!"

10 / 10
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6 Report
  • Kel...
  • Taken for less than 1 month
  • June 16, 2021

Tadalafil "I started taking Cialis for Raynaud's about 1 week ago. I do already notice a difference in the blood flow to my hands and feet, however, the daily headaches and muscle aches in my legs make me question if it's worth taking. I'll wait it out a few more weeks to see if the side effects lessen."

5 / 10
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4 Report
  • Raz...
  • Taken for 1 to 2 years
  • January 3, 2021

Tadalafil for Erectile Dysfunction "I'm 40 years old, mild ED past few years. First 5mg dose I took, it was solid as a rock within 1/2 hour, felt very full and stayed hard as long as I wanted, didn't want it to stop, was like a new toy. Was able to j/o 3 times that day and then get down to it with the other half that night with the same rock-solid hardness every single time. I j/o a lot as I have a higher sex drive. Definitely makes it look bigger when flaccid and the slightest bit of arousal can get it solid if I want it to. Incredible morning wood every day. Headache and lower back ache when taking for the first 3 months but now 12 months of use and no side effects."

10 / 10
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216 Report
  • rea...
  • December 30, 2020

For Erectile Dysfunction "So having seen our sex life become nonexistent (I'm 58 years old and my wife is 60) and masturbating only occasionally. I visited the pharmacist with my 'problem.' Was given 5mg tadalafil daily. Took 1 before bed and woke to go to the toilet with a nice bulge in my pajama bottoms and had a nice full erection (that had not happened for years). Went back to sleep and woke early again with a full, hard erection - my wife noticed too, so we had sex. This was great as my erection lasted longer and I noticed I took longer to ejaculate. My orgasm was intense too. During the day, I noticed I kept getting random erections, which my wife noticed. However, I did get a slight headache and stuffy nose for the next couple of days. So I dropped the dose down to 5mg every other day, and now no side effects, but still find erections at night and in the morning to be full and firm, so now sex life is great and love getting an erection and going to the bathroom to masturbate. Getting the dose right is the key."

10 / 10
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10 Report
  • Den...
  • December 24, 2020

Tadalafil for Erectile Dysfunction "An occasional ED problem led to low confidence. I tried 20 mg, which worked well but had a headache for 3 days. After much research, started taking Cialis 2.5 mg daily with no side effects. Couldn't be happier. Highly recommend."

10 / 10
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18 Report
  • GWa...
  • Taken for 1 to 2 years
  • September 1, 2020

For Erectile Dysfunction "Updated: I am 50 years old. I take 9 mg once a week prior to solo sexual activity for prostate health. Best results are in the first 5 to 36 hours. Erections are satisfactorily firm, but at my age, I still require proper direct stimulation and mental arousal. What I like is that during a long session, my body can naturally relax to a safe, partial erection and then regain full engorgement when I am ready for orgasm. Side effects are minor nasal congestion and headache during the first 6 hours. My primary care provider cautioned me to watch for a drop in blood pressure (dizziness) or an uncomfortable erection. My penis is quite firm during orgasm and ejaculation, and as a result, I typically allow a few extra minutes of post-climax recovery time while my penis slowly becomes flaccid."

8 / 10
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10 Report
  • BJa...
  • Taken for 6 months to 1 year
  • August 21, 2020

For Erectile Dysfunction "I have used other ED prescriptions before and have always had side effects like blurred vision and headaches. With tadalafil, there have been no side effects, and when taken early, it seems to last until the next morning, of course, you need some stimulation to help it out. Being on Medicare, it is less expensive than other ED drugs. (Physical shape: age 70, overweight, little activity, BMI 38, retired, 1-2 times a week)"

9 / 10
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8 Report
  • Red...
  • Taken for 1 to 6 months
  • July 22, 2020

Tadalafil for Benign Prostatic Hyperplasia "I wrote earlier that adding the 0.5 mg Cialis combined with the 40 mg Flomax gave me great results. But, the side effects (which a number of people have reported here) were a big problem. Bad backaches and headaches after about 3 days of use. But great results with urinary problems of BPH. So I had to quit the Cialis for a few days to get it out of my system. Then started one half of a pill, every other day, thinking that I will increase as needed. Well, never needed to increase. In other words, a quarter dose. And great results! Only get up once a night to pee! First time for that in decades. Also, although I didn’t have a lot of problems with erections for my age, 75, yes, it did improve that too. With just a quarter dose. And no side effects. I have been on this regimen now for about 3 months. All good! PS. Initially, my insurance wouldn’t cover Tadalafil, but my doctor called and explained that it was for BPH, and now they cover it."

10 / 10
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36 Report
  • Red...
  • Taken for less than 1 month
  • April 23, 2020

Tadalafil for Benign Prostatic Hyperplasia "Take Flomax for BPH. So-so results with Flomax. Added 0.5 Tadalafil with good results in 1 day. By the 3rd day, had to stop due to bad back pain and headache. Have stopped now for a day, 35 hours since last dose, and pain is gone. I will now try one dose every other day. Will come back to site with results. Great to have all this info. Thanks."

8 / 10
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29 Report
  • Ron...
  • Taken for less than 1 month
  • March 13, 2020

For Erectile Dysfunction "Took it for the first time, one 5 mg pill a day. After my first 3 days, I woke up early in the morning and fell back down due to dizziness and headaches. Got concerned and went to get a thorough check, on which all was good. The dizziness has lingered over 7 days, as well as headaches. This mess is dangerous and did the opposite."

1 / 10
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11 Report

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